在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMOD1 Antibody

  • 中文名稱:
    TMOD1兔多克隆抗體
  • 貨號:
    CSB-PA023909LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, A549 whole cell lysate
      All lanes: TMOD1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41, 27 kDa
      Observed band size: 41 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TMOD1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMOD1
  • 別名:
    Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod), TMOD1, D9S57E TMOD
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tropomodulin-1 protein (105-359aa)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,TMOD1 Antibody (CSB-PA023909LA01HU),的標記方式是Non-conjugated。對于TMOD1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA023909LB01HU TMOD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA023909LC01HU TMOD1 Antibody, FITC conjugated
    Biotin CSB-PA023909LD01HU TMOD1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
  • 基因功能參考文獻:
    1. Tmod1 function in mouse and human erythroblasts, was investigated. PMID: 28729432
    2. The mutation reduced binding affinity for both Lmod2 and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies . PMID: 26873245
    3. Study highlighted a novel TMOD1-mediated link between NF-kappaB activation and MMP13 induction, which accounts in part for the NF-kappaB-dependent malignant phenotype of TNBC. PMID: 25398440
    4. Tmod1 and Tmod3 showed somewhat different tropomyosin-binding site utilization. PMID: 24922351
    5. The structures and biochemical analysis of structure-inspired mutants showed that one Tmod molecule interacts with three actin subunits at the pointed end, while also contacting two tropomyosin molecules on each side of the filament. PMID: 25061212
    6. Tropomyosin requires an intact N-terminal coiled coil to interact with this protein PMID: 11964245
    7. levels of TM1, TM2 and TM3 are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase-signaling pathway PMID: 15095301
    8. The N-terminal "KRK ring" may participate in balancing electrostatic force with hydrophobic interaction in dimerization of TM and its binding to E-Tmod. PMID: 16297372
    9. study identifies several amino acid residues on Tmod-1 that are important for its interaction with TM5 (a nonmuscle TM isoform) PMID: 16434395

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Tropomodulin family
  • 組織特異性:
    Highly expressed in the erythrocyte, heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 11871

    OMIM: 190930

    KEGG: hsa:7111

    STRING: 9606.ENSP00000259365

    UniGene: Hs.404289



主站蜘蛛池模板: 亚洲a∨国产av综合av下载 | 亚洲在av人极品无码| 久久九九精品国产av片国产| 亚洲综合中文字幕无线码| 影音先锋女人av鲁色资源网久久 | 人妻无码一区二区三区| 热久久美女精品天天吊色| 久久国产福利一区二区| 亚洲欧美日韩国产自偷| 精品无码黑人又粗又大又长| 亚洲国产美女精品久久久久∴| 国产精品国产三级国产av麻豆| 中国老妇xxxx性开放| 99久久99久久精品国产片果冻| 欧美真人性野外做爰| 免费人成网站在线观看视频| 人与嘼av免费| 国产精品久久久久久久久久久不卡| 欧美成人精品三级一二三在线观看| 免费无遮挡在线观看网站| 天干夜天干天天天爽视频| 精品国产乱码久久久人妻| 久久亚洲精品无码爱剪辑| 俺去俺来也www色官网| 日本免费大黄在线观看| 亚洲爆乳无码专区www| 国产97人妻人人做人碰人人爽| 欧美搡bbbbb搡bbbbb| 亚洲欧美精品伊人久久| 影音先锋男人站| 国产超碰人人模人人爽人人喊| 激情按摩系列片aaaa| 伊人www22综合色| 久久中文精品无码中文字幕| 日韩不卡1卡2卡三卡网站| 亚洲视频在线观看| 精品蜜臀av在线天堂| 精品无码久久久久久尤物| 无码日韩精品一区二区人妻| 色悠久久久久综合欧美99| 国产亚洲精品自在久久蜜tv|