在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMOD1 Antibody

  • 中文名稱:
    TMOD1兔多克隆抗體
  • 貨號:
    CSB-PA023909GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    TMOD1
  • 別名:
    D9S57E antibody; E Tmod antibody; E tropomodulin antibody; E-Tmod antibody; Erythrocyte tropomodulin antibody; ETMOD antibody; MGC124125 antibody; MGC124126 antibody; OTTHUMP00000021743 antibody; TMOD antibody; Tmod1 antibody; TMOD1 protein antibody; TMOD1_HUMAN antibody; Tropomodulin 1 antibody; Tropomodulin-1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TMOD1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
  • 基因功能參考文獻(xiàn):
    1. Tmod1 function in mouse and human erythroblasts, was investigated. PMID: 28729432
    2. The mutation reduced binding affinity for both Lmod2 and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies . PMID: 26873245
    3. Study highlighted a novel TMOD1-mediated link between NF-kappaB activation and MMP13 induction, which accounts in part for the NF-kappaB-dependent malignant phenotype of TNBC. PMID: 25398440
    4. Tmod1 and Tmod3 showed somewhat different tropomyosin-binding site utilization. PMID: 24922351
    5. The structures and biochemical analysis of structure-inspired mutants showed that one Tmod molecule interacts with three actin subunits at the pointed end, while also contacting two tropomyosin molecules on each side of the filament. PMID: 25061212
    6. Tropomyosin requires an intact N-terminal coiled coil to interact with this protein PMID: 11964245
    7. levels of TM1, TM2 and TM3 are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase-signaling pathway PMID: 15095301
    8. The N-terminal "KRK ring" may participate in balancing electrostatic force with hydrophobic interaction in dimerization of TM and its binding to E-Tmod. PMID: 16297372
    9. study identifies several amino acid residues on Tmod-1 that are important for its interaction with TM5 (a nonmuscle TM isoform) PMID: 16434395

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Tropomodulin family
  • 組織特異性:
    Highly expressed in the erythrocyte, heart and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11871

    OMIM: 190930

    KEGG: hsa:7111

    STRING: 9606.ENSP00000259365

    UniGene: Hs.404289



主站蜘蛛池模板: 狠狠做五月深爱婷婷伊人| 一本天堂v无码亚洲道久久| 国产成人一区二区三区免费视频| 日韩亚洲欧美中文高清在线| 一本一本久久aa综合精品| 久久精品人妻一区二区三区| 国产精品丝袜亚洲熟女| 国产乱了伦视频大全亚琴影院| 久久丫精品久久丫| 久久精品人妻一区二区三区| 亚洲乱码中文论理电影 | 成人性三级欧美在线观看| 国产亚洲精品视觉盛宴| 中文字幕亚洲情99在线| 久久欧美国产伦子伦精品| 日韩欧无码一区二区三区免费不卡 | 欧美精品videossex少妇| 国产高清av首播原创麻豆| 久久精品66免费99精品| 无码人妻专区免费视频| 内射白浆一区二区在线观看 | 狠狠色婷婷久久综合频道毛片 | 99在线精品免费视频九九视| 伊人久久大香线蕉综合5g| 人人爽人人爽人人片av亚洲 | 大伊香蕉在线精品视频75| 亚洲va在线∨a天堂va欧美va | 久久人人超碰精品caoporen | 人妻无码中文字幕永久在线| 久久av无码精品人妻糸列| 少妇做爰免费视看片| 国产欧美综合在线观看第十页| 亚洲 欧美 唯美 国产 伦 综合| 18禁黄污吃奶免费看网站| 亚洲暴爽av天天爽日日碰| 婷婷成人小说综合专区| 日韩精品视频一区二区三区| 人与禽交av在线播放| 麻豆国产成人av在线播放欲色| 美女扒开大腿让男人桶| 青娱乐极品视觉盛宴av|