在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TMOD1 Antibody, FITC conjugated

TMOD1 Antibody, FITC conjugated

  • 中文名稱：
    TMOD1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA023909LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TMOD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMOD1
  • 別名：
    Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod), TMOD1, D9S57E TMOD
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Tropomodulin-1 protein (105-359aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
  • 基因功能參考文獻(xiàn)：
    1. Tmod1 function in mouse and human erythroblasts, was investigated. PMID: 28729432
    2. The mutation reduced binding affinity for both Lmod2 and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies . PMID: 26873245
    3. Study highlighted a novel TMOD1-mediated link between NF-kappaB activation and MMP13 induction, which accounts in part for the NF-kappaB-dependent malignant phenotype of TNBC. PMID: 25398440
    4. Tmod1 and Tmod3 showed somewhat different tropomyosin-binding site utilization. PMID: 24922351
    5. The structures and biochemical analysis of structure-inspired mutants showed that one Tmod molecule interacts with three actin subunits at the pointed end, while also contacting two tropomyosin molecules on each side of the filament. PMID: 25061212
    6. Tropomyosin requires an intact N-terminal coiled coil to interact with this protein PMID: 11964245
    7. levels of TM1, TM2 and TM3 are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase-signaling pathway PMID: 15095301
    8. The N-terminal "KRK ring" may participate in balancing electrostatic force with hydrophobic interaction in dimerization of TM and its binding to E-Tmod. PMID: 16297372
    9. study identifies several amino acid residues on Tmod-1 that are important for its interaction with TM5 (a nonmuscle TM isoform) PMID: 16434395

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomodulin family
  • 組織特異性：
    Highly expressed in the erythrocyte, heart and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11871

    OMIM: 190930

    KEGG: hsa:7111

    STRING: 9606.ENSP00000259365

    UniGene: Hs.404289



主站蜘蛛池模板： 亚洲精品99久久久久中文字幕| 中日韩va无码中文字幕| 国产成人高清精品亚洲| 国内老熟妇乱子伦视频| 亚洲国产精品久久精品| 亚洲欧美日韩中文无线码| 亚洲成av大片大片在线播放| 亚洲精品人成网线在播放va| 拍真实国产伦偷精品| 大桥久未无码吹潮在线观看 | 国产午夜福利在线播放| 97久久久人妻一区精品| 亚洲欧美自拍制服另类图区| 婷婷丁香六月激情综合啪 | 亚洲人成77777在线播放网站不卡 国产 | 欧洲野花视频天堂视频p 亚洲aⅴ天堂av天堂无码 | 国产一区二区三区精品视频| 久久久久久免费毛片精品| 国产男生午夜福利免费网站 | 久久天天躁狠狠躁夜夜2019| 亚洲国产成人无码网站大全| 亚洲国产成人久久一区二区三区| 日韩人妻熟女中文字幕aⅴ春菜| 狼友网精品视频在线观看| 9lporm自拍视频区| 中文字幕无码第1页| 免费看国产曰批40分钟| 夫前人妻被灌醉侵犯在线| 亚州中文字幕午夜福利电影| 小妖精又紧又湿高潮h视频69| 狂野av人人澡人人添| 本道久久综合无码中文字幕| 国产 亚洲 制服 无码 中文 | 亚洲精品久久yy5099| 国产亚洲欧洲aⅴ综合一区| 性视频播放免费视频| 亚洲中文字幕精品久久久久久动漫| 狠狠狠色丁香综合婷婷久久| 天堂中文在线8最新版地址 | 婷婷综合久久中文字幕| 国产日韩精品一区二区三区在线| 国产精品综合一区二区三区|