在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TMOD1 Antibody, HRP conjugated

TMOD1 Antibody, HRP conjugated

  • 中文名稱：
    TMOD1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA023909LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TMOD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMOD1
  • 別名：
    Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod), TMOD1, D9S57E TMOD
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tropomodulin-1 protein (105-359aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
  • 基因功能參考文獻：
    1. Tmod1 function in mouse and human erythroblasts, was investigated. PMID: 28729432
    2. The mutation reduced binding affinity for both Lmod2 and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies . PMID: 26873245
    3. Study highlighted a novel TMOD1-mediated link between NF-kappaB activation and MMP13 induction, which accounts in part for the NF-kappaB-dependent malignant phenotype of TNBC. PMID: 25398440
    4. Tmod1 and Tmod3 showed somewhat different tropomyosin-binding site utilization. PMID: 24922351
    5. The structures and biochemical analysis of structure-inspired mutants showed that one Tmod molecule interacts with three actin subunits at the pointed end, while also contacting two tropomyosin molecules on each side of the filament. PMID: 25061212
    6. Tropomyosin requires an intact N-terminal coiled coil to interact with this protein PMID: 11964245
    7. levels of TM1, TM2 and TM3 are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase-signaling pathway PMID: 15095301
    8. The N-terminal "KRK ring" may participate in balancing electrostatic force with hydrophobic interaction in dimerization of TM and its binding to E-Tmod. PMID: 16297372
    9. study identifies several amino acid residues on Tmod-1 that are important for its interaction with TM5 (a nonmuscle TM isoform) PMID: 16434395

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomodulin family
  • 組織特異性：
    Highly expressed in the erythrocyte, heart and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 11871

    OMIM: 190930

    KEGG: hsa:7111

    STRING: 9606.ENSP00000259365

    UniGene: Hs.404289



主站蜘蛛池模板： 国产沙发午睡系列999| 无码中字出轨中文人妻中文中 | 免费纯肉3d动漫无码网站| 亚洲老妇色熟女老太| 山东熟女啪啪哦哦叫| 国产精品爆乳奶水无码视频免费| 国产 | 欧洲野花视频欧洲1| 国产精品一区在线蜜臀| 亚洲图片综合图区20p| 极品人妻videosss人妻| 久久这里只有精品首页| 人人妻人人添人人爽欧美一区| 国产98色在线 | 国| 理论片午午伦夜理片影院| 东京一本一道一二三区| √天堂中文最新版在线中文| 少妇粗大进出白浆嘿嘿视频| 久9re热视频这里只有精品| 无翼乌工口肉肉无遮挡无码18| 成视频年人黄网站视频福利| 精品日韩亚洲欧美高清a| 国产乱码二卡3卡四卡| 精品国产青草久久久久福利| 狠狠色噜噜狠狠狠888米奇视频 | 精品黑人一区二区三区久久| 午夜福利体验免费体验区| 色综合a怡红院怡红院| 国产福利一区二区三区在线视频| 欧美牲交a欧美牲交aⅴ久久| 亚洲综合色区在线观看| 亚洲欧美综合国产精品二区| 国产成av人片久青草影院| 午夜福利92国语| 亚洲成a人片在线不卡一二三区| 尤物yw193无码点击进入| 西西人体444www大胆无码视频 | 日本少妇高潮喷水视频| 3d动漫精品啪啪一区二区中| 麻豆国产精成人品观看免费| 精品无人区无码乱码毛片国产 | 国产精品色情国产三级在|