在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMED2 Antibody

  • 中文名稱:
    TMED2兔多克隆抗體
  • 貨號:
    CSB-PA05049A0Rb
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: TMED2 antibody at 6µg/ml
      Lane 1: HCT116 whole cell lysate
      Lane 2: Mouse ovarian tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 23 kDa
      Observed band size: 23 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA05049A0Rb at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA05049A0Rb at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TMED2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMED2
  • 別名:
    coated vesicle membrane protein antibody; Membrane protein p24A antibody; p24 antibody; p24 family protein beta-1 antibody; P24A antibody; p24beta1 antibody; RNP24 antibody; Sid 394 antibody; Sid394 antibody; TMED2 antibody; TMED2_HUMAN antibody; transmembrane emp24 domain trafficking protein 2 antibody; Transmembrane emp24 domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Transmembrane emp24 domain-containing protein 2 protein (26-111AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,TMED2 Antibody (CSB-PA05049A0Rb),的標記方式是Non-conjugated。對于TMED2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA05049B0Rb TMED2 Antibody, HRP conjugated ELISA
    FITC CSB-PA05049C0Rb TMED2 Antibody, FITC conjugated
    Biotin CSB-PA05049D0Rb TMED2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
  • 基因功能參考文獻:
    1. Surface plasmon resonance and solution NMR analyses revealed that p24beta1 and p24delta1 GOLD domains interact weakly (Kd= ~10(-4)M). PMID: 27569046
    2. TMED2/p24beta1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. PMID: 22212250
    3. Both p24A transmembrane protein and p23 are specific cargo receptors of G protein-coupled receptors (GPCR) and differentially regulate GPCR signaling in astrocytes. PMID: 21219331
    4. These results suggest that p24A is the limiting factor in CaSR trafficking in the early secretory pathway, and that cycling between the ER and ERGIC protects CaSR from degradation. PMID: 20361938
    5. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    EMP24/GP25L family
  • 數據庫鏈接:

    HGNC: 16996

    KEGG: hsa:10959

    STRING: 9606.ENSP00000262225

    UniGene: Hs.733403



主站蜘蛛池模板: 国产伦精品一区二区三区免费| 很色很爽很黄裸乳视频| 久久欧美国产伦子伦精品 | 亚洲久热中文字幕在线| 亚洲精品久久久久久久久久久捆绑| www.一区二区三区在线 | 欧洲 | 好爽别插了无码视频| 中文韩国午夜理伦三级好看| 亚洲国产超清无码专区| 国产精品麻豆成人av电影艾秋| 国产精品无码翘臀在线观看| 2012中文字幕在线视频| 免费无码又爽又刺激成人| 久久精品亚洲精品无码| 国产女人18毛片水真多| 鲁一鲁一鲁一鲁一澡| 国产精品毛片完整版视频| 亚洲精品无码av人在线观看国产| 蜜臀av在线观看| 蜜臀av午夜一区二区三区| 亚洲欧美综合国产精品二区| 国产乱子伦在线一区二区| 中文字幕人成乱码熟女| 色欲av无码一区二区三区| 国产成人亚洲综合网站小说| 精品免费国产一区二区三区四区介绍| 精品影片在线观看的网站 | 俺去俺来也www色官网| 国产乱人伦av麻豆网| 亚洲精品无码av专区最新| 精品午夜中文字幕熟女人妻在线| 国产精品毛片大码女人| 国产精品自在在线午夜| 无码h肉动漫在线观看免费| 黄桃av无码免费一区二区三区| 男ji大巴进入女人的视频小说| 亚洲中文字幕av无码区| 视频二区丝袜国产欧美日韩| 少妇人妻真实偷人精品视频| 人妻被按摩师玩弄到潮喷| 无码精品国产一区二区免费|