在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMED2 Antibody

  • 中文名稱:
    TMED2兔多克隆抗體
  • 貨號:
    CSB-PA023658GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TMED2
  • 別名:
    coated vesicle membrane protein antibody; Membrane protein p24A antibody; p24 antibody; p24 family protein beta-1 antibody; P24A antibody; p24beta1 antibody; RNP24 antibody; Sid 394 antibody; Sid394 antibody; TMED2 antibody; TMED2_HUMAN antibody; transmembrane emp24 domain trafficking protein 2 antibody; Transmembrane emp24 domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TMED2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
  • 基因功能參考文獻:
    1. Surface plasmon resonance and solution NMR analyses revealed that p24beta1 and p24delta1 GOLD domains interact weakly (Kd= ~10(-4)M). PMID: 27569046
    2. TMED2/p24beta1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. PMID: 22212250
    3. Both p24A transmembrane protein and p23 are specific cargo receptors of G protein-coupled receptors (GPCR) and differentially regulate GPCR signaling in astrocytes. PMID: 21219331
    4. These results suggest that p24A is the limiting factor in CaSR trafficking in the early secretory pathway, and that cycling between the ER and ERGIC protects CaSR from degradation. PMID: 20361938
    5. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    EMP24/GP25L family
  • 數據庫鏈接:

    HGNC: 16996

    KEGG: hsa:10959

    STRING: 9606.ENSP00000262225

    UniGene: Hs.733403



主站蜘蛛池模板: 亚洲日韩av一区二区三区四区 | 亚洲国产精品第一区二区| 少妇三级全黄| 国产精品无码综合区| 最新69成人精品视频免费| 国产裸体xxxx视频| 巨爆乳中文字幕爆乳区| 国产超碰人人爱被ios解锁| 在线人视频观看免费| 色欲久久久中文字幕综合网| 亚洲色欧美色2019在线| 97久久超碰亚洲视觉盛宴| 日本丰满少妇高潮呻吟| 不卡高清av手机在线观看| 久久精品国产99国产精2021| 少妇无码吹潮| 欧美z0zo人禽交欧美人禽交| 中文字幕乱码一区二区免费| 波多野结衣办公室33分钟| 强奷乱码中文字幕熟女导航| 国产成人午夜福利在线观看| 国产麻豆一精品av一免费软件| 成人午夜特黄aaaaa片男男| 国产成人艳妇aa视频在线| 国产亚洲精品久久久久久小说| 手机在线亚洲国产精品| 亚洲大尺度无码专区尤物| 国产麻豆放荡av剧情演绎| 久久婷婷五月综合色首页| 国产精品免费视频色拍拍| 少妇被爽到高潮喷水久久欧美精品 | 无码精品日韩专区| 最美女人体内射精一区二区| 免费国偷自产拍精品视频| 中文字幕v亚洲ⅴv天堂| 无码av片在线观看免费| 无码人妻丰满熟妇奶水区码| 欧美成人看片黄a免费看| 欧美村妇激情内射| 亚洲精品av一区午夜福利| 国产精品久久久久无码av|