在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transmembrane emp24 domain-containing protein 2 (TMED2), partial

  • 中文名稱:
    人TMED2重組蛋白
  • 貨號:
    CSB-YP618982HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TMED2重組蛋白
  • 貨號:
    CSB-EP618982HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TMED2重組蛋白
  • 貨號:
    CSB-EP618982HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TMED2重組蛋白
  • 貨號:
    CSB-BP618982HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TMED2重組蛋白
  • 貨號:
    CSB-MP618982HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TMED2
  • Uniprot No.:
  • 別名:
    coated vesicle membrane protein; Membrane protein p24A; p24; p24 family protein beta-1; P24A; p24beta1; RNP24; Sid 394; Sid394; TMED2; TMED2_HUMAN; transmembrane emp24 domain trafficking protein 2 ; Transmembrane emp24 domain-containing protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
  • 基因功能參考文獻:
    1. Surface plasmon resonance and solution NMR analyses revealed that p24beta1 and p24delta1 GOLD domains interact weakly (Kd= ~10(-4)M). PMID: 27569046
    2. TMED2/p24beta1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. PMID: 22212250
    3. Both p24A transmembrane protein and p23 are specific cargo receptors of G protein-coupled receptors (GPCR) and differentially regulate GPCR signaling in astrocytes. PMID: 21219331
    4. These results suggest that p24A is the limiting factor in CaSR trafficking in the early secretory pathway, and that cycling between the ER and ERGIC protects CaSR from degradation. PMID: 20361938
    5. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    EMP24/GP25L family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16996

    KEGG: hsa:10959

    STRING: 9606.ENSP00000262225

    UniGene: Hs.733403



主站蜘蛛池模板: 一二三四社区在线中文视频| 国模大胆一区二区三区| 久久精品国产最新地址| 非洲黑人性xxxx精品| 美女露出奶头扒开尿口视频直播 | 亚洲国产婷婷六月丁香| 国产精品亚洲w码日韩中文| 在线观看的av免费网站| 欧美熟妇性xxxx欧美熟人多毛| 少妇被猛男粗大的猛进出| 成人爱做日本视频免费| 亚洲色偷偷偷网站色偷一区| 国内精品一区二区三区| 欧美日韩精品人妻狠狠躁免费视频| 狼色精品人妻在线视频免费| 欧美性猛交xxxxx按摩欧美 | 日本三级欧美三级人妇视频| 五十路熟女一区二区三区| 暖暖视频日本在线观看| 特黄做受又硬又粗又大视频小说| 国内少妇偷人精品视频| 欧美丰满熟妇xxxx性ppx人交| 特级做a爰片毛片免费看108| 国产亚洲精品久久久久9999| 国产一区二区丝袜高跟鞋| 成在线人永久免费视频播放| 99久无码中文字幕一本久道| 性av盈盈无码天堂| 少妇精品无码一区二区免费视频| 久久精品人妻少妇一区二区三区| 久久久综合九色综合鬼色| 久热这里只有精品12| 亚洲色偷拍另类无码专区| 人人澡人摸人人添| 国产爽视频在线观看视频| 国产热の有码热の无码视频| 无码人妻一区二区三区一| 成人自慰女黄网站免费大全| 亚洲中文字幕无码永久在线不卡 | 西西人体大胆瓣开下部毛茸茸| 色综合a怡红院怡红院|