在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMED2 Antibody, HRP conjugated

  • 中文名稱:
    TMED2兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA05049B0Rb
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TMED2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMED2
  • 別名:
    coated vesicle membrane protein antibody; Membrane protein p24A antibody; p24 antibody; p24 family protein beta-1 antibody; P24A antibody; p24beta1 antibody; RNP24 antibody; Sid 394 antibody; Sid394 antibody; TMED2 antibody; TMED2_HUMAN antibody; transmembrane emp24 domain trafficking protein 2 antibody; Transmembrane emp24 domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane emp24 domain-containing protein 2 protein (26-111AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
  • 基因功能參考文獻:
    1. Surface plasmon resonance and solution NMR analyses revealed that p24beta1 and p24delta1 GOLD domains interact weakly (Kd= ~10(-4)M). PMID: 27569046
    2. TMED2/p24beta1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. PMID: 22212250
    3. Both p24A transmembrane protein and p23 are specific cargo receptors of G protein-coupled receptors (GPCR) and differentially regulate GPCR signaling in astrocytes. PMID: 21219331
    4. These results suggest that p24A is the limiting factor in CaSR trafficking in the early secretory pathway, and that cycling between the ER and ERGIC protects CaSR from degradation. PMID: 20361938
    5. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    EMP24/GP25L family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16996

    KEGG: hsa:10959

    STRING: 9606.ENSP00000262225

    UniGene: Hs.733403



主站蜘蛛池模板: 亚洲精品国产精品国产自2022| 无码无套少妇毛多69xxx| 又色又爽又高潮免费视频观看| 老妇女性较大毛片| 少妇做爰免费视频网站| 2012中文字幕在线视频| 国产亚洲精品第一综合不卡 | 欧美国产精品久久久乱码| 久久狼人大香伊蕉国产| 无码喷水一区二区浪潮av| 最近中文av字幕在线中文 | 亚洲精品无码aⅴ中文字幕蜜桃| 极品少妇高潮到爽| 婷婷五月综合缴情在线视频| 四虎影成人精品a片| 精品爆乳一区二区三区无码av | 精品久久久无码中文字幕天天| 国产成人拍精品视频午夜网站| 久久99精品久久久久久动态图| 丰满少妇作爱视频免费观看| 人妻久久久精品99系列2021| 久久99日韩国产精品久久99| 一卡二卡3卡四卡网站精品| 狠狠噜天天噜日日噜| 中国少妇无码专区| 丰满大爆乳波霸奶| 亚洲 日韩 欧美 有码 在线| 欧美人妻久久精品| 免费国产裸体美女视频全黄| 久久久久成人精品免费播放动漫| 色狠狠色噜噜av天堂一区| 中文字幕亚洲制服在线看| 久久亚洲精品无码观看不卡| 日本xxxx裸体xxxx视频大全| 激情人妻另类人妻伦| 爽爽精品dvd蜜桃成熟时电影院| 无码av中文字幕免费放| 亚洲欧美v国产蜜芽tv| 亚洲综合日韩av无码毛片| 亚欧免费无码aⅴ在线观看| 少妇把腿扒开让我爽爽视频|