在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMED2 Antibody, HRP conjugated

  • 中文名稱:
    TMED2兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA05049B0Rb
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TMED2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMED2
  • 別名:
    coated vesicle membrane protein antibody; Membrane protein p24A antibody; p24 antibody; p24 family protein beta-1 antibody; P24A antibody; p24beta1 antibody; RNP24 antibody; Sid 394 antibody; Sid394 antibody; TMED2 antibody; TMED2_HUMAN antibody; transmembrane emp24 domain trafficking protein 2 antibody; Transmembrane emp24 domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane emp24 domain-containing protein 2 protein (26-111AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
  • 基因功能參考文獻:
    1. Surface plasmon resonance and solution NMR analyses revealed that p24beta1 and p24delta1 GOLD domains interact weakly (Kd= ~10(-4)M). PMID: 27569046
    2. TMED2/p24beta1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. PMID: 22212250
    3. Both p24A transmembrane protein and p23 are specific cargo receptors of G protein-coupled receptors (GPCR) and differentially regulate GPCR signaling in astrocytes. PMID: 21219331
    4. These results suggest that p24A is the limiting factor in CaSR trafficking in the early secretory pathway, and that cycling between the ER and ERGIC protects CaSR from degradation. PMID: 20361938
    5. p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 PMID: 17693410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    EMP24/GP25L family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16996

    KEGG: hsa:10959

    STRING: 9606.ENSP00000262225

    UniGene: Hs.733403



主站蜘蛛池模板: 国产肉丝袜视频在线观看| 亚洲精品乱码久久久久久蜜桃不卡| 亚洲人成网站日本片| 麻豆专媒体一区二区| 中国真实偷乱视频| 精品人妻一区二区三区浪潮在线| 亚洲天堂2017无码中文| 丁香五月综合久久激情| 亚洲欧美日韩中文在线制服| 国产精品欧美一区二区三区不卡| 人人妻一区二区三区| 一本一道久久综合久久| 国产av无码专区亚汌a√| 久久精品国产99国产精品亚洲| 性无码专区无码片| 欧美日韩精品成人网站二区| 中文字幕被公侵犯的漂亮人妻 | 人妻有码av中文字幕久久琪| 男女爽爽午夜18污污影院| 日本人妻精品免费视频| 国产成人精品一区二区三区免费| 人妻aⅴ无码一区二区三区| 动漫无遮挡羞视频在线观看| 久久精品国产清高在天天线| 国产丝袜美女一区二区三区| 亚洲深深色噜噜狠狠爱网站| 国色天香精品一卡2卡3卡4| 久久精品女人天堂av免费观看| 人人妻人人澡人人爽人人精品av| 色综合欧美亚洲国产| 欧美 亚洲 日韩 中文2019| 亚洲人成无码网站久久99热国产 | 伊人久久大香线蕉av一区二区| 欧美videos另类极品| 18级成人毛片免费观看| 高清中文字幕在线a片| 亚洲综合小说另类图片五月天| 白嫩少妇bbw撒尿视频| 一区二区视频| 在线综合亚洲欧洲综合网站 | 怡红院av亚洲一区二区三区h|