在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SV2C Antibody

SV2C Antibody

  • 中文名稱：
    SV2C兔多克隆抗體
  • 貨號：
    CSB-PA022980LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA022980LA01HU diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA022980LA01HU diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SV2C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SV2C
  • 別名：
    SV2C antibody; KIAA1054 antibody; Synaptic vesicle glycoprotein 2C antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SV2C Antibody (CSB-PA022980LA01HU)，的標記方式是Non-conjugated。對于SV2C Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA022980LB01HU SV2C Antibody, HRP conjugated ELISA
    FITC CSB-PA022980LC01HU SV2C Antibody, FITC conjugated
    Biotin CSB-PA022980LD01HU SV2C Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
  • 基因功能參考文獻：
    1. These data establish SV2C as a mediator of dopamine neuron function and suggest that SV2C disruption is a unique feature of PD that likely contributes to dopaminergic dysfunction. PMID: 28246328
    2. N-linked glycosylation of SV2C is required for binding and uptake of botulinum neurotoxin A. PMID: 27294781
    3. Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions. PMID: 25282537
    4. A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials. PMID: 25117820
    5. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a selective increase of SV2C in sprouting mossy fibres. PMID: 23617838
    6. The fact that multiple SNPs in SV2C may impact response to atypical antipsychotics suggests that further evaluation of SNPs in this gene PMID: 23886675
    7. high-resolution crystal structure of the BoNT/A receptor-binding domain in complex with the SV2C luminal domain PMID: 24240280

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30670

    OMIM: 610291

    KEGG: hsa:22987

    STRING: 9606.ENSP00000423541

    UniGene: Hs.646953



主站蜘蛛池模板： 国产嫖妓风韵犹存对白| 亚洲午夜精品久久久久久app| 久久婷婷国产综合精品| 极品少妇被后入内射视| 亚洲va无码va在线va天堂| 丝袜熟女国偷自产中文字幕亚洲 | 亚洲va久久久噜噜噜久久| 一二三四在线观看免费视频| 一本色道av久久精品+网站| 亚洲人成无码网站18禁10| 亚洲精品自产拍在线观看亚瑟| 又大又硬又黄的免费视频| 极品少妇被啪到呻吟喷水| 中年人妻丰满av无码久久不卡| 亚洲性线免费观看视频成熟| 国产欧美日本亚洲精品一5区| 欧美人妻精品一区二区三区| 国产精品96久久久久久| 亚洲国产综合av在线观看 | 亚洲第一在线综合网站| 日韩少妇内射免费播放18禁裸乳| 国产午夜精品理论片| 国产人妻精品区一区二区三区| 2020国产精品午夜福利在线观看| 五月av综合av国产av| 久久不见久久见免费影院www日本| 成人午夜无码精品免费看| 初尝黑人巨砲波多野结衣| 九九九免费观看视频| 青草伊人久久综在合线亚洲观看 | 高清国产av一区二区三区| 亚洲综合另类小说色区一| 大肉大捧一进一出好爽动态图 | 中文人妻av久久人妻18| 国产超碰人人做人人爽av| 男人女人做爽爽18禁网站| 国产精品美女被遭强扒开双腿 | 欧亚乱熟女一区二区三区在线| 国产丰满人妻一区二区| 久久综合久久久久88| 国产亚洲精品久久久久久久软件|