在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SV2C Antibody

  • 中文名稱:
    SV2C兔多克隆抗體
  • 貨號:
    CSB-PA022980GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SV2C
  • 別名:
    SV2C antibody; KIAA1054 antibody; Synaptic vesicle glycoprotein 2C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SV2C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
  • 基因功能參考文獻:
    1. These data establish SV2C as a mediator of dopamine neuron function and suggest that SV2C disruption is a unique feature of PD that likely contributes to dopaminergic dysfunction. PMID: 28246328
    2. N-linked glycosylation of SV2C is required for binding and uptake of botulinum neurotoxin A. PMID: 27294781
    3. Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions. PMID: 25282537
    4. A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials. PMID: 25117820
    5. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a selective increase of SV2C in sprouting mossy fibres. PMID: 23617838
    6. The fact that multiple SNPs in SV2C may impact response to atypical antipsychotics suggests that further evaluation of SNPs in this gene PMID: 23886675
    7. high-resolution crystal structure of the BoNT/A receptor-binding domain in complex with the SV2C luminal domain PMID: 24240280

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily
  • 數據庫鏈接:

    HGNC: 30670

    OMIM: 610291

    KEGG: hsa:22987

    STRING: 9606.ENSP00000423541

    UniGene: Hs.646953



主站蜘蛛池模板: 亚洲中文字幕无码中文字在线| 大香线蕉伊人精品超碰| 9久9久女女热精品视频在线观看| 国产山东熟女48嗷嗷叫| 久久婷婷成人综合色综合| 东京热一区二区三区无码视频| 国产人妻高清国产拍精品| 久久亚洲精品无码av宋| 国产精品视频二区不卡| 人妻体体内射精一区二区| 韩国午夜福利片在线观看| 亚洲偷精品国产五月丁香麻豆| 被黑人猛躁10次高潮视频| 日韩欧美人妻一区二区三区| 久久综合给综合给久久| 亚洲精品一区二区国产精华液 | 久久青草成人综合网站| 欧美日韩亚洲国产欧美电影 | 无码中文字幕日韩专区| 亚洲人成精品久久久久桥| 亚洲国产精品久久久久4婷婷 | 成人婷婷网色偷偷亚洲男人的天堂| 日韩av影院在线观看| 亚洲黑人巨大videos| 午夜亚洲影院在线观看| 无码任你躁久久久久久| 色婷婷综合久久久久中文字幕| 香蕉欧美成人精品a∨在线观看| 亚洲色大成网站www永久在线观看| 亚洲熟伦熟女新五十路熟妇| 婷婷五月深深久久精品| 亚洲 日韩 欧美 成人 在线| 婷婷色五月开心五月| 日欧一片内射va在线影院| 成人影片麻豆国产影片免费观看| 久久久久国产精品人妻aⅴ四季| 日本xxxxx片免费观看喷水| 亚洲视频在线观看| 国产天堂久久天堂av色综合| 亚洲色爱免费观看视频| 亚州av综合色区无码一区|