在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SV2C Antibody

SV2C Antibody

  • 中文名稱：
    SV2C兔多克隆抗體
  • 貨號(hào)：
    CSB-PA004707
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using SV2C Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SV2C
  • 別名：
    SV2C antibody; KIAA1054 antibody; Synaptic vesicle glycoprotein 2C antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human SV2C.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
  • 基因功能參考文獻(xiàn)：
    1. These data establish SV2C as a mediator of dopamine neuron function and suggest that SV2C disruption is a unique feature of PD that likely contributes to dopaminergic dysfunction. PMID: 28246328
    2. N-linked glycosylation of SV2C is required for binding and uptake of botulinum neurotoxin A. PMID: 27294781
    3. Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions. PMID: 25282537
    4. A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials. PMID: 25117820
    5. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a selective increase of SV2C in sprouting mossy fibres. PMID: 23617838
    6. The fact that multiple SNPs in SV2C may impact response to atypical antipsychotics suggests that further evaluation of SNPs in this gene PMID: 23886675
    7. high-resolution crystal structure of the BoNT/A receptor-binding domain in complex with the SV2C luminal domain PMID: 24240280

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30670

    OMIM: 610291

    KEGG: hsa:22987

    STRING: 9606.ENSP00000423541

    UniGene: Hs.646953



主站蜘蛛池模板： 99久久99视频只有精品| 午夜福利体验免费体验区| 办公丝袜av一区二区三区| 欧美人与动性xxxxbbbb | 黑人巨茎大战欧美白妇免费| 久久超碰97人人做人人爱| 日韩亚洲国产综合高清| 天堂最新版在线www官网中文地址| 亚洲日本在线电影| av色综合久久天堂av色综合在 | 国内精品久久久久久久影视| 日本欧美亚洲中文在线观看| 亚洲人成黄网站69影院| 欧美群交射精内射颜射潮喷| 色综合久久蜜芽国产精品| 国产嫖妓风韵犹存对白| 亚洲aⅴ永久无码一区二区三区| 国内精品久久久久久久影视麻豆 | 激情综合一区二区三区| 国产国语老龄妇女a片| 国产乱了真实在线观看| 美女裸奶100%无遮挡免费网站| 国产办公室秘书无码精品99| 亚洲人成网线在线播放va蜜芽| 国产中文欧美日韩在线| 久章草国语自产拍在线观看| 日本一卡2卡3卡4卡5卡精品视频| 亚洲精品第一区二区三区| 韩日午夜在线资源一区二区| 日韩精品av一区二区三区| 中文字幕乱码一区二区免费| 国产亚洲精品成人aa片| 国产免费无遮挡吸奶头视频| 久久亚洲精品无码网站| 爆乳高潮喷水无码正在播放| 国产精品无码午夜福利| 麻豆精品国产精华精华液好用吗| 日本道免费精品一区二区| 国内极度色诱视频网站| 精品人妻av区乱码| 国产精成人品|