在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SV2C Antibody, FITC conjugated

  • 中文名稱:
    SV2C兔多克隆抗體, FITC偶聯(lián)
  • 貨號:
    CSB-PA022980LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SV2C Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SV2C
  • 別名:
    SV2C antibody; KIAA1054 antibody; Synaptic vesicle glycoprotein 2C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
  • 基因功能參考文獻:
    1. These data establish SV2C as a mediator of dopamine neuron function and suggest that SV2C disruption is a unique feature of PD that likely contributes to dopaminergic dysfunction. PMID: 28246328
    2. N-linked glycosylation of SV2C is required for binding and uptake of botulinum neurotoxin A. PMID: 27294781
    3. Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions. PMID: 25282537
    4. A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials. PMID: 25117820
    5. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a selective increase of SV2C in sprouting mossy fibres. PMID: 23617838
    6. The fact that multiple SNPs in SV2C may impact response to atypical antipsychotics suggests that further evaluation of SNPs in this gene PMID: 23886675
    7. high-resolution crystal structure of the BoNT/A receptor-binding domain in complex with the SV2C luminal domain PMID: 24240280

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily
  • 數(shù)據(jù)庫鏈接:

    HGNC: 30670

    OMIM: 610291

    KEGG: hsa:22987

    STRING: 9606.ENSP00000423541

    UniGene: Hs.646953



主站蜘蛛池模板: 亚洲精品无码一区二区| 国产作爱视频免费播放| 国产偷国产偷亚洲高清app| 欧美日韩中文国产一区发布| 精品人妻人人做人人爽| 嫖妓丰满肥熟妇在线精品| 曰本极品少妇videossexhd | 无码人妻一区二区三区在线视频| 欧美性欧美巨大黑白大战| 欧美片内射欧美美美妇| 久九九精品免费视频| 国内精品伊人久久久久网站| 无卡无码无免费毛片| 四川少妇大战4黑人| 久久免费精品国产72精品| 小12萝裸体自慰出白浆| 太粗太深了太紧太爽了动态图男男| 在线精品国产成人综合| 亚洲经典三级| 一本之道高清乱码久久久| 国产xxxx色视频在线观看| 免费无码又爽又刺激毛片| 性无码专区无码| 免费无码不卡视频在线观看| 久久五十路丰满熟女中出| 亚洲 卡通 欧美 制服 中文 | 日本无遮挡吸乳视频| 风流老熟女一区二区三区| 国产成人久久综合77777| 亚洲成a人片在线观看的电影| 无码人妻精品一二三区免费| 天天天欲色欲色www免费| 欧美一道本一区二区三区| 永久中文字幕免费视频网站| 国产精品无码一区二区三区在 | а√天堂资源中文在线官网| 99久视频只有精品2019| 日韩精品无码熟人妻视频| 欧美人妻aⅴ中文字幕| 国产偷国产偷亚洲清高| 亚洲熟妇av一区二区三区宅男|