在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPDL1 Antibody

SPDL1 Antibody

  • 中文名稱：
    SPDL1兔多克隆抗體
  • 貨號：
    CSB-PA477766
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: CSB-PA477766(SPDL1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SPDL1
  • 別名：
    AA409762 antibody; Arsenite related gene 1 protein antibody; Arsenite-related gene 1 protein antibody; CCDC 99 antibody; Ccdc99 antibody; Coiled coil domain containing 99 antibody; Coiled-coil domain-containing protein 99 antibody; FLJ20364 antibody; FLJ40690 antibody; hSpindly antibody; MGC124977 antibody; Protein Spindly antibody; rhabdomyosarcoma antigen MU RMS 40.4A antibody; Rhabdomyosarcoma antigen MU-RMS-40.4A antibody; Rrhabdomyosarcoma antigen protein MU RMS 40.4A antibody; SPDL1 antibody; SPDLY_HUMAN antibody; Spindle apparatus coiled coil domain containing protein 1 antibody; Spindle apparatus coiled coil protein 1 antibody; Spindly antibody; Spindly homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human SPDL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 基因功能參考文獻：
    1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression PMID: 25808490
    2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization. PMID: 25825516
    3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules. PMID: 20427577
    4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing PMID: 20439434
    5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B. PMID: 19468067

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
  • 蛋白家族：
    Spindly family
  • 數據庫鏈接：

    HGNC: 26010

    OMIM: 616401

    KEGG: hsa:54908

    STRING: 9606.ENSP00000265295

    UniGene: Hs.368710



主站蜘蛛池模板： 久久97久久97精品免视看| 强插女教师av在线| 少妇被粗大的猛烈进出图片| 性夜影院午夜看片| 最近高清中文在线字幕在线观看1| 国产精品免费久久久久软件| 婷婷五月综合缴情在线视频| 人妻少妇heyzo无码专区| 亚洲成av人片不卡无码久久| 久久人人97超碰国产精品| 亚洲精品中国国产嫩草影院美女| 人人爽人人片人人片av| 酒店大战丝袜高跟鞋人妻| 国产av夜夜欢一区二区三区| 中字幕视频在线永久在线| 亚洲а∨天堂男人色无码| 国产成人一区二区三区| 欧美猛少妇色xxxxx猛叫| 日韩一区二区三区射精| 99精品无人区乱码1区2区3区| 国产色爱av资源综合区| 可以看三级的网站| 亚洲另类欧美综合在线| 欧美性猛交xxxx三人| 99久久99久久免费精品蜜桃| 国产精品自产拍高潮在线观看 | 欧美大肥婆大肥bbbbb| 亚洲国产激情一区二区三区| 色哟哟最新在线观看入口| 曰本av中文字幕一区二区| 无码人妻精品一区二区在线视频 | 欧美老妇与zozozo交| 国产aⅴ视频免费观看| 免费人成视频在线播放视频| 亚洲精品国偷拍自产在线观看蜜桃 | 东京热无码av一区二区| 国产成人vr精品a视频| 国产精品久久人妻无码网站蜜臀| 麻豆果冻传媒2021精品传媒一区下载 | 婷婷久久久亚洲欧洲日产国码av | 日本高清在线天码一区播放|