在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPDL1 Antibody, Biotin conjugated

SPDL1 Antibody, Biotin conjugated

  • 中文名稱：
    SPDL1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA842662LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SPDL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SPDL1
  • 別名：
    AA409762 antibody; Arsenite related gene 1 protein antibody; Arsenite-related gene 1 protein antibody; CCDC 99 antibody; Ccdc99 antibody; Coiled coil domain containing 99 antibody; Coiled-coil domain-containing protein 99 antibody; FLJ20364 antibody; FLJ40690 antibody; hSpindly antibody; MGC124977 antibody; Protein Spindly antibody; rhabdomyosarcoma antigen MU RMS 40.4A antibody; Rhabdomyosarcoma antigen MU-RMS-40.4A antibody; Rrhabdomyosarcoma antigen protein MU RMS 40.4A antibody; SPDL1 antibody; SPDLY_HUMAN antibody; Spindle apparatus coiled coil domain containing protein 1 antibody; Spindle apparatus coiled coil protein 1 antibody; Spindly antibody; Spindly homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein Spindly protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 基因功能參考文獻：
    1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression PMID: 25808490
    2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization. PMID: 25825516
    3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules. PMID: 20427577
    4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing PMID: 20439434
    5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B. PMID: 19468067

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
  • 蛋白家族：
    Spindly family
  • 數據庫鏈接：

    HGNC: 26010

    OMIM: 616401

    KEGG: hsa:54908

    STRING: 9606.ENSP00000265295

    UniGene: Hs.368710



主站蜘蛛池模板： 女人被强╳到高潮喷水在线观看| 亚洲日韩a∨无码久| 久久99精品久久久久久蜜芽 | 97久久精品人人槡人妻人 | 狠狠色噜噜狠狠狠狠777米奇| 亚洲最大成人一区久久久| 亚洲精品久久av无码一区二区| 少妇富婆高级按摩出水高潮| 波多野结衣办公室双飞| 国产精品无码av天天爽| 亚洲孰妇无码av在线播放| 久久久久久人妻精品一区| 无码精品人妻一区二区三区漫画| 色综合av男人的天堂伊人| 亚洲最大激情中文字幕| 国产麻无矿码直接观看| 一本一道波多野结衣av黑人| 国产在线观看黄av免费| 成人无码午夜在线观看| 国产av一区二区三区日韩| 精品一区二区三区东京热| 国产亚洲精品久久久久久无 | 亚洲熟妇色xxxxx欧美老妇y| 亚洲一区二区观看播放| 欧美黑人巨大videos精品男男 | 免费观看在线a毛片| 国产精品久久久久无码av1| 无码日韩人妻精品久久蜜桃| 99精品国产兔费观看久久| 大又大粗又爽又黄少妇毛片免费| 亚洲午夜成人av电影| 黑人粗长大战亚洲女| 精品国产免费第一区二区三区| 国产成人综合久久免费导航| 苍井空浴缸大战猛男120分钟| 久久精品农村毛片| 国产果冻豆传媒麻婆精东| 日韩精品无码一区二区三区久久久 | 亚洲综合色区无码专区| 久久99er精品国产首页| 久本草在线中文字幕亚洲|