在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPDL1 Antibody

SPDL1 Antibody

  • 中文名稱：
    SPDL1兔多克隆抗體
  • 貨號：
    CSB-PA167401
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, mouse testis tissue, Jurkat cells, Primary antibody: CSB-PA167401(SPDL1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SPDL1
  • 別名：
    AA409762 antibody; Arsenite related gene 1 protein antibody; Arsenite-related gene 1 protein antibody; CCDC 99 antibody; Ccdc99 antibody; Coiled coil domain containing 99 antibody; Coiled-coil domain-containing protein 99 antibody; FLJ20364 antibody; FLJ40690 antibody; hSpindly antibody; MGC124977 antibody; Protein Spindly antibody; rhabdomyosarcoma antigen MU RMS 40.4A antibody; Rhabdomyosarcoma antigen MU-RMS-40.4A antibody; Rrhabdomyosarcoma antigen protein MU RMS 40.4A antibody; SPDL1 antibody; SPDLY_HUMAN antibody; Spindle apparatus coiled coil domain containing protein 1 antibody; Spindle apparatus coiled coil protein 1 antibody; Spindly antibody; Spindly homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human SPDL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 基因功能參考文獻：
    1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression PMID: 25808490
    2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization. PMID: 25825516
    3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules. PMID: 20427577
    4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing PMID: 20439434
    5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B. PMID: 19468067

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
  • 蛋白家族：
    Spindly family
  • 數據庫鏈接：

    HGNC: 26010

    OMIM: 616401

    KEGG: hsa:54908

    STRING: 9606.ENSP00000265295

    UniGene: Hs.368710



主站蜘蛛池模板： 久久99日韩国产精品久久99| 色综合色狠狠天天综合色| 97人妻无码一区二区精品免费| 欧洲-级毛片内射| 最近中文字幕免费mv在线视频| 香草乱码一二三四区别| 裸身美女无遮挡永久免费视频 | 天堂在线观看www| 久久99精品久久久久久齐齐| 亚洲精品成人久久电影网| 日本无码人妻一区二区色欲| 人妻丰满熟妇av无码区| 无码免费无线观看在线视频| 美乳丰满人妻无码视频| 最新亚洲一卡二卡三卡四卡| 国产95在线 | 亚洲| 艳妇乳肉豪妇荡乳xxx| 国产二级一片内射视频播放| 国产麻豆精品福利在线| 99国产精品久久久久久久久久久| 少妇扒开粉嫩小泬视频| 国产在线精品99一卡2卡| 丰满又黄又爽少妇毛片| 国内精品久久久久久久小说| 50岁退休熟女露脸高潮| 精品国产一区二区三区久久狼| 亚洲综合久久成人a片| 无码人妻久久久一区二区三区| 中文在线а√在线| 亚洲日韩日本中文在线| 国产成人精品无码a区在线观看| 曰曰摸夜夜添夜夜添高潮出水| 亚洲国产精品无码久久一线| 日韩国产成人无码av毛片蜜柚| 亚洲欧美在线观看| 熟女少妇精品一区二区| 免费无遮挡很爽很污很黄的网站 | 被窝影院午夜无码国产| 久久中文字幕无码专区| 在线精品一区二区三区| 最新精品露脸国产在线|