在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPDL1 Antibody, FITC conjugated

SPDL1 Antibody, FITC conjugated

  • 中文名稱：
    SPDL1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA842662LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SPDL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SPDL1
  • 別名：
    AA409762 antibody; Arsenite related gene 1 protein antibody; Arsenite-related gene 1 protein antibody; CCDC 99 antibody; Ccdc99 antibody; Coiled coil domain containing 99 antibody; Coiled-coil domain-containing protein 99 antibody; FLJ20364 antibody; FLJ40690 antibody; hSpindly antibody; MGC124977 antibody; Protein Spindly antibody; rhabdomyosarcoma antigen MU RMS 40.4A antibody; Rhabdomyosarcoma antigen MU-RMS-40.4A antibody; Rrhabdomyosarcoma antigen protein MU RMS 40.4A antibody; SPDL1 antibody; SPDLY_HUMAN antibody; Spindle apparatus coiled coil domain containing protein 1 antibody; Spindle apparatus coiled coil protein 1 antibody; Spindly antibody; Spindly homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein Spindly protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 基因功能參考文獻：
    1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression PMID: 25808490
    2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization. PMID: 25825516
    3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules. PMID: 20427577
    4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing PMID: 20439434
    5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B. PMID: 19468067

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
  • 蛋白家族：
    Spindly family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26010

    OMIM: 616401

    KEGG: hsa:54908

    STRING: 9606.ENSP00000265295

    UniGene: Hs.368710



主站蜘蛛池模板： av在线 亚洲 天堂| 欧美老妇bbbwwbbbww| 欧美亚洲色aⅴ大片| 久久精品无码一区二区www| 欧美黑人又粗又大又爽免费| 国产无遮挡aaa片爽爽| 成人aa免费视频在线播放| 国产成人精品日本亚洲| 真实国产乱子伦对白在线播放| 中文字幕亚洲欧美日韩在线不卡| 高清无码视频直接看| 国产亚洲精品无码不卡| 欧美成人午夜免费影院手机在线看 | 国产精品亚洲欧美中字| 亚洲人成影院在线观看| 亚洲三区在线观看内射后入| 午夜男女无遮掩免费视频| 亚洲中文字幕无码av在线| av无码精品一区二区三区宅噜噜| 日韩中文高清在线专区| 熟女人妻高清一区二区三区| 中国6一12呦女精品| 香港三级日本三级妇三级| 日日橹狠狠爱欧美视频| 色99久久久久高潮综合影院| 特大巨黑吊xxxx高潮| 人人模人人爽人人喊久久| 色窝窝免费播放视频在线| 人人人妻人人澡人人爽欧美一区 | 2021国产精品视频网站| 97精品尹人久久大香线蕉 | 久久久无码精品亚洲日韩蜜桃| 狠人干练合综合网| 国产午夜鲁丝片av无码| 人妻无码视频一区二区三区| 亚洲中文字幕丝祙制服| 天天鲁在视频在线观看| 久久亚洲精品成人av| 亚洲国产精品无码久久青草| 无码a∨高潮抽搐流白浆| 成年女人毛片免费视频|