在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPDL1 Antibody

SPDL1 Antibody

  • 中文名稱：
    SPDL1兔多克隆抗體
  • 貨號：
    CSB-PA030153
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using CCDC99 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SPDL1
  • 別名：
    AA409762 antibody; Arsenite related gene 1 protein antibody; Arsenite-related gene 1 protein antibody; CCDC 99 antibody; Ccdc99 antibody; Coiled coil domain containing 99 antibody; Coiled-coil domain-containing protein 99 antibody; FLJ20364 antibody; FLJ40690 antibody; hSpindly antibody; MGC124977 antibody; Protein Spindly antibody; rhabdomyosarcoma antigen MU RMS 40.4A antibody; Rhabdomyosarcoma antigen MU-RMS-40.4A antibody; Rrhabdomyosarcoma antigen protein MU RMS 40.4A antibody; SPDL1 antibody; SPDLY_HUMAN antibody; Spindle apparatus coiled coil domain containing protein 1 antibody; Spindle apparatus coiled coil protein 1 antibody; Spindly antibody; Spindly homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human CCDC99.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 基因功能參考文獻：
    1. Farnesylation of Spindly is essential for its localization, & thus for proper localization of dynein & dynactin, to prometaphase kinetochores. Both Spindly and CENP-E farnesylation are required for efficient chromosome congression PMID: 25808490
    2. hSpindly is farnesylated in vivo and farnesylation is essential for its interaction with the RZZ complex and hence Kinetochore localization. PMID: 25825516
    3. Spindly is not only required for kinetochore localization of dynein but is a functional component of a mechanism that couples dynein-dependent poleward movement of chromosomes to their efficient attachment to microtubules. PMID: 20427577
    4. dynein-mediated removal of Spindly from microtubule-attached kinetochores, rather than poleward transport per se, is the critical reaction in checkpoint silencing PMID: 20439434
    5. [hSpindly] Localization of human Spindly (hSpindly) to kinetochores is controlled by the Rod/Zw10/Zwilch (RZZ) complex and Aurora B. PMID: 19468067

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
  • 蛋白家族：
    Spindly family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26010

    OMIM: 616401

    KEGG: hsa:54908

    STRING: 9606.ENSP00000265295

    UniGene: Hs.368710



主站蜘蛛池模板： 国产奶头好大揉着好爽视频 | 成人无码视频免费播放| 伊人色合天天久久综合网| 色翁荡熄又大又硬又粗又动态图| 一本一本久久a久久精品综合| 国产99久一区二区三区a片| 亚洲国产欧美国产综合久久| 无线日本视频精品| 天堂va视频一区二区| 少妇人妻在线视频| 精品国产一区二区三区av性色| 国产真实乱对白精彩| 国产一二三四区乱码免费| 四虎国产精品永久地址入口| 国色天香社区在线视频| 亚洲爆乳少妇无码激情| 亚洲色欲一区二区三区在线观看| 久久中文字幕人妻av熟女| 色欲天天天综合网| 欧美丰满熟妇多毛xxxxx| 在线亚洲人成电影网站色www| 性按摩xxxx在线观看| 日韩在线一区二区不卡视频| 人妻系列无码一区二区三区| 国产裸体舞一区二区三区| 国产老妇伦国产熟女老妇视频 | 九九久久精品国产av片国产| 日本午夜免费啪视频在线| 国产成人精品无码一区二区三区| 白丝爆浆18禁一区二区三区 | 欧美欧洲成本大片免费| 国产 | 久你欧洲野花视频欧洲1| www插插插无码视频网站| 午夜性色福利在线观看视频| 精品人妻伦一二三区久久aaa片 | 久久久久久久久久久免费精品| 亚洲熟女乱色一区二区三区| 国产成人av大片大片在线播放| 无码专区—va亚洲v天堂麻豆| 中文字幕va一区二区三区| 国产精品久久久久久av|