在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLU7 Antibody

  • 中文名稱:
    SLU7兔多克隆抗體
  • 貨號:
    CSB-PA021783GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    9G8 antibody; hSlu7 antibody; MGC9280 antibody; Pre mRNA splicing factor SLU7 antibody; Pre-mRNA-splicing factor slu7 antibody; SLU 7 antibody; slu7 antibody; SLU7 splicing factor homolog (S. cerevisiae) antibody; SLU7 splicing factor homolog antibody; SLU7_HUMAN antibody; splicing factor antibody; Step II splicing factor SLU7 antibody; Zinc knuckle motif containing antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SLU7
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
  • 基因功能參考文獻:
    1. these findings indicate that SLU7 is co-opted by hepatocellular carcinoma (HCC) cells and other tumor cell types to maintain survival, and identify this splicing regulator as a new determinant for the expression of the oncogenic miR-17-92 cluster. This novel mechanism may be exploited for the development of antitumoral strategies in cancers displaying such SLU7-miR-17-92 crosstalk PMID: 26804174
    2. SLU7 knockdown in liver cells resulted in profound changes in pre-mRNA splicing and gene expression, leading to impaired glucose and lipid metabolism, refractoriness to key metabolic hormones, and reversion to a fetal-like gene expression pattern. PMID: 24865429
    3. These observations together point to an altered recruitment and dependence on SLU7, suggesting its role in facilitating transitions that promote catalysis, and highlight the diversity in spliceosome assembly. PMID: 23754748
    4. RBM22 and hSlu7 differ significantly in their subcellular distributions under stress conditions, and RBM22 enhances the cytoplasmic translocation of hSlu7 under stress. PMID: 21122810
    5. The zinc-knuckle motif of hSlu7 determines the cellular localization of the protein through a nucleocytoplasmic-sensitive shuttling balance. PMID: 15181151
    6. hSlu7 has a broad effect on alternative splicing PMID: 15728250
    7. Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing PMID: 17804646

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族:
    SLU7 family
  • 數據庫鏈接:

    HGNC: 16939

    OMIM: 605974

    KEGG: hsa:10569

    STRING: 9606.ENSP00000297151

    UniGene: Hs.435342



主站蜘蛛池模板: 777奇米四色成人影视色区| 粗大猛烈进出高潮视频免费看 | 亚洲免费观看在线视频| 国产内射老熟女aaaa∵| 午夜精品久久久久久久四虎| 性按摩无码中文| 精品人妻无码一区二区色欲产成人 | 人妻在线无码一区二区三区| www国产无套内射com| 久久久成人精品av四区| 亚洲 欧美 另类 综合 日韩| 亚洲精品无码鲁网午夜| 又粗又大内射免费视频小说| 狠狠躁夜夜躁人人爽蜜桃| 福利视频一二三在线观看| 色偷偷一区二区无码视频| 精品久久久久久人妻无码中文字幕| 国产精品多p对白交换绿帽| 一区二三区国产好的精华液o9 | 亚洲国产精品综合久久20| 免费的很黄很污的视频| 久久精品国产久精国产果冻传媒| 大战丰满无码人妻50p| 熟女内射v888av| 久久国内精品自在自线| 亚洲 卡通 欧美 制服 中文| 欧美日韩在线视频一区| 无码人中文字幕| 学生妹无套内射正在播放 | 久久无码中文字幕无码| 国产牛仔裤网站精品| 国产精品婷婷久久爽一下| 国产草莓精品国产av片国产| 99精品国产在热久久无毒| 免费裸体无遮挡黄网站免费看| 免费无码又爽又刺激网站| 成av人电影在线观看| 成人免费毛片内射美女app| 国产精品中文久久久久久久| 97午夜理论片在线影院| 无码国产精品高清免费|