在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLU7 Antibody

SLU7 Antibody

  • 中文名稱：
    SLU7兔多克隆抗體
  • 貨號：
    CSB-PA021783LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, Mouse brain tissue
      All lanes: SLU7 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 69 kDa
      Observed band size: 69 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA021783LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA021783LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA021783LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLU7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    9G8 antibody; hSlu7 antibody; MGC9280 antibody; Pre mRNA splicing factor SLU7 antibody; Pre-mRNA-splicing factor slu7 antibody; SLU 7 antibody; slu7 antibody; SLU7 splicing factor homolog (S. cerevisiae) antibody; SLU7 splicing factor homolog antibody; SLU7_HUMAN antibody; splicing factor antibody; Step II splicing factor SLU7 antibody; Zinc knuckle motif containing antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Pre-mRNA-splicing factor SLU7 protein (138-310AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SLU7 Antibody (CSB-PA021783LA01HU)，的標記方式是Non-conjugated。對于SLU7 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA021783LB01HU SLU7 Antibody, HRP conjugated ELISA
    FITC CSB-PA021783LC01HU SLU7 Antibody, FITC conjugated
    Biotin CSB-PA021783LD01HU SLU7 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
  • 基因功能參考文獻：
    1. these findings indicate that SLU7 is co-opted by hepatocellular carcinoma (HCC) cells and other tumor cell types to maintain survival, and identify this splicing regulator as a new determinant for the expression of the oncogenic miR-17-92 cluster. This novel mechanism may be exploited for the development of antitumoral strategies in cancers displaying such SLU7-miR-17-92 crosstalk PMID: 26804174
    2. SLU7 knockdown in liver cells resulted in profound changes in pre-mRNA splicing and gene expression, leading to impaired glucose and lipid metabolism, refractoriness to key metabolic hormones, and reversion to a fetal-like gene expression pattern. PMID: 24865429
    3. These observations together point to an altered recruitment and dependence on SLU7, suggesting its role in facilitating transitions that promote catalysis, and highlight the diversity in spliceosome assembly. PMID: 23754748
    4. RBM22 and hSlu7 differ significantly in their subcellular distributions under stress conditions, and RBM22 enhances the cytoplasmic translocation of hSlu7 under stress. PMID: 21122810
    5. The zinc-knuckle motif of hSlu7 determines the cellular localization of the protein through a nucleocytoplasmic-sensitive shuttling balance. PMID: 15181151
    6. hSlu7 has a broad effect on alternative splicing PMID: 15728250
    7. Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing PMID: 17804646

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族：
    SLU7 family
  • 數據庫鏈接：

    HGNC: 16939

    OMIM: 605974

    KEGG: hsa:10569

    STRING: 9606.ENSP00000297151

    UniGene: Hs.435342



主站蜘蛛池模板： 国产成人夜色高潮福利影视| 国产精品无码专区久久久| 伊人久久丁香色婷婷啪啪| 女人被狂躁高潮啊的视频在线看 | 国产高清女同学巨大乳在线观看 | 国产清纯美女爆白浆视频| 老熟女老太婆爽| 国产精品亚韩精品无码a在线| 99久久精品国产一区二区三区| 麻豆视传媒精品av| 蜜桃少妇av久久久久久久| 天天天天躁天天爱天天碰2018| 波多野结衣 黑人| 拍拍拍无挡免费视频| 五 月 丁 香 综合中文| 国产免费永久精品无码| 强行交换配乱婬bd| 日日噜噜大屁股熟妇| 熟妇的奶头又大又粗视频| 特大巨黑吊xxxx高潮| 国产又色又爽又黄好看的视频| 亚洲精品卡一卡三卡四卡乱码| 中文字幕日韩一区二区不卡| 亚洲日本一区二区一本一道| 欧美成人精品福利视频| 五月激情婷婷丁香综合基地| 人妻夜夜添夜夜无码av| 日本不卡三区| 少妇精品偷拍高潮少妇小说| av电影在线观看| 精品一区精品二区制服| 国产白丝无码免费视频| 一区二区三区av高清免费波多| 欧美顶级少妇作爱| 亚洲精品专区在线观看| 国产精品毛片av999999| 青青草视频在线观看| 久久久久无码中| 欧美亚洲国产第一精品久久| 五月天中文字幕mv在线| 久久久无码人妻精品一区|