在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLU7 Antibody, FITC conjugated

  • 中文名稱:
    SLU7兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA021783LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLU7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    9G8 antibody; hSlu7 antibody; MGC9280 antibody; Pre mRNA splicing factor SLU7 antibody; Pre-mRNA-splicing factor slu7 antibody; SLU 7 antibody; slu7 antibody; SLU7 splicing factor homolog (S. cerevisiae) antibody; SLU7 splicing factor homolog antibody; SLU7_HUMAN antibody; splicing factor antibody; Step II splicing factor SLU7 antibody; Zinc knuckle motif containing antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Pre-mRNA-splicing factor SLU7 protein (138-310AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
  • 基因功能參考文獻:
    1. these findings indicate that SLU7 is co-opted by hepatocellular carcinoma (HCC) cells and other tumor cell types to maintain survival, and identify this splicing regulator as a new determinant for the expression of the oncogenic miR-17-92 cluster. This novel mechanism may be exploited for the development of antitumoral strategies in cancers displaying such SLU7-miR-17-92 crosstalk PMID: 26804174
    2. SLU7 knockdown in liver cells resulted in profound changes in pre-mRNA splicing and gene expression, leading to impaired glucose and lipid metabolism, refractoriness to key metabolic hormones, and reversion to a fetal-like gene expression pattern. PMID: 24865429
    3. These observations together point to an altered recruitment and dependence on SLU7, suggesting its role in facilitating transitions that promote catalysis, and highlight the diversity in spliceosome assembly. PMID: 23754748
    4. RBM22 and hSlu7 differ significantly in their subcellular distributions under stress conditions, and RBM22 enhances the cytoplasmic translocation of hSlu7 under stress. PMID: 21122810
    5. The zinc-knuckle motif of hSlu7 determines the cellular localization of the protein through a nucleocytoplasmic-sensitive shuttling balance. PMID: 15181151
    6. hSlu7 has a broad effect on alternative splicing PMID: 15728250
    7. Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing PMID: 17804646

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族:
    SLU7 family
  • 數據庫鏈接:

    HGNC: 16939

    OMIM: 605974

    KEGG: hsa:10569

    STRING: 9606.ENSP00000297151

    UniGene: Hs.435342



主站蜘蛛池模板: 国产边摸边吃奶边做爽视频| 亚洲区日韩精品中文字幕| 亲子乱子伦xxxx视频| 国产欧美一区二区精品久久久 | 人妻无码中文专区久久五月婷| 亚洲精品一区久久久久一品av| 欧美性猛交xxxx免费看| 伦理片午夜视频在线观看| 国产成人无码a区在线观看视频app| 欧美丰满熟妇bbb久久久| 久久99精品久久久久久动态图| 国产精品99久久免费| 国产精品aⅴ视频在线播放 | 久久人人97超碰国产精品| 少妇裸体性生交| 夜鲁鲁鲁夜夜综合视频欧美| 亚洲欧美日韩中文播放| 韩国 日本 亚洲 国产 不卡| 国产人妻精品午夜福利免费| 久久亚洲国产精品成人av秋霞| 九九热线精品视频16| 国内午夜熟妇又乱又伦| 一个人看的www片免费高清视频 | 人摸人人人澡人人超碰97| 蜜臀av色欲a片无码一区二区| 国产又黄又猛又粗又爽的a片动漫| 亚洲久久中文字幕www网站| 欧洲精品无码一区二区三区在线播放| 日韩一区二区三区无码人妻视频| 人妻大战黑人白浆狂泄| 国产精品老汉av| 精品多人p群无码| 在线精品国产成人综合| 国产精品无码素人福利| 国产高清视频色拍| 日韩欧美亚洲国产精品字幕久久久| 无码人妻啪啪一区二区| 精品无人区码一码二码三码区别| 性色香蕉av久久久天天网 | 亚洲级αv无码毛片久久精品| 精品服丝袜无码视频一区 |