在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC25A12 Antibody

SLC25A12 Antibody

  • 中文名稱：
    SLC25A12兔多克隆抗體
  • 貨號(hào)：
    CSB-PA000919
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HEPG2 cells using ARALAR Polyclonal Antibody
    • Western Blot analysis of various cells using ARALAR Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SLC25A12
  • 別名：
    SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ARALAR.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
  • 基因功能參考文獻(xiàn)：
    1. Genetic variants of SLC25A12 may be associated with risks for childhood ASD. PMID: 28536923
    2. The features of AGC1 structure and function in physiology and pathology, regulation by calcium, dependency on mitochondrial membrane potential, role in cancer cells, and tissue specificity are reviewed. AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Review. PMID: 27132995
    3. Sensitivity analyses including only studies with family-based design demonstrated significant association between autism spectrum disorders and SNPs rs2292813 and rs2056202. In contrast, sensitivity analyses including case-control design studies only failed to find a significant association. Review. PMID: 25663199
    4. rs2056202 and rs2292813 in SLC25A12 may contribute significantly to autism spectrum disorders risk. PMID: 25921325
    5. Structure of the calcium bound and calcium free N- and C-terminal domains is described, elucidating the mechanism of calcium regulation. PMID: 25410934
    6. The physiological roles of AGC1, its links to calcium homeostasis, and its involvement in autism pathogenesis, are reviewed. PMID: 21691713
    7. This study found no differences in the allele, genotype, or haplotype frequencies of these two SNPs between patients and controls. PMID: 19913066
    8. Variants of the AGC1-encoding SLC25A12 gene were neither correlated with AGC activation nor associated with autism-spectrum disorders in 309 simplex and 17 multiplex families. PMID: 18607376
    9. SLC25A12 gene is linked to autism PMID: 15056512
    10. Aralar1 has a role in determining glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells PMID: 15494407
    11. These results suggest that SLC25A12 is not a major contributor to autism risk in these families. PMID: 16648338
    12. it is unlikely that the SLC25A12 polymorphisms investigated play a substantial role in conferring susceptibility to schizophrenia PMID: 17693006
    13. rs2056202 polymorphism in SLC25A12 may be associated with levels of routines and rituals in autism and related disorders PMID: 17894412
    14. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. PMID: 18180767
    15. SLC25A12 gene is associated with autism. PMID: 19360665

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Epileptic encephalopathy, early infantile, 39 (EIEE39)
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性：
    Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10982

    OMIM: 603667

    KEGG: hsa:8604

    STRING: 9606.ENSP00000388658

    UniGene: Hs.470608



主站蜘蛛池模板： 四虎永久在线精品免费视频观看| 182tv午夜福利在线地址二| 一区二区三区人妻无码| 欧洲极品少妇| 亚洲国产区男人本色| 国产亚洲精品a片久久久| 亚洲国产品综合人成综合网站| 人妻无码vs中文字幕久久av爆| 国产模特嫩模私拍视频在线| 超碰国产精品人人做人人爱| 肉大捧一进一出免费视频| 亚洲精品久久久久久下一站| 精品一区二区三区免费播放| 国产精品51麻豆cm传媒 | 久久精品国产欧美日韩99热 | 中文字幕人妻被公上司喝醉506 | 特级西西人体444www高清大胆| 中文在线www天堂网| 亚洲国产成人久久精品99| 国产午夜高清高清在线观看| 久久―日本道色综合久久 | 在线欧美日韩制服国产| 曰本丰满熟妇xxxx性| 国产a国产片国产| 国产69久久精品成人看| 网友自拍区视频精品| 免费观看的av在线播放| 亚洲精品成人无码中文毛片| 亚洲在线国产日韩欧美| 99久久久无码国产精品免费| 午夜精品久久久内射近拍高清 | 精品熟女少妇av免费久久| 欧美超级乱婬视频播放| 玩超薄丝袜人妻的经历| 美女视频黄频a美女大全| 亚洲五月丁香综合视频| 亚洲成a人片在线观看无码专区| 无码成人一区二区| 精品综合久久久久久888蜜芽| 亚洲午夜久久久影院伊人| 99热精品久久只有精品|