在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC25A12 Antibody, Biotin conjugated

SLC25A12 Antibody, Biotin conjugated

  • 中文名稱：
    SLC25A12兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA021478LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC25A12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC25A12
  • 別名：
    SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Calcium-binding mitochondrial carrier protein Aralar1 protein (202-317AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
  • 基因功能參考文獻：
    1. Genetic variants of SLC25A12 may be associated with risks for childhood ASD. PMID: 28536923
    2. The features of AGC1 structure and function in physiology and pathology, regulation by calcium, dependency on mitochondrial membrane potential, role in cancer cells, and tissue specificity are reviewed. AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Review. PMID: 27132995
    3. Sensitivity analyses including only studies with family-based design demonstrated significant association between autism spectrum disorders and SNPs rs2292813 and rs2056202. In contrast, sensitivity analyses including case-control design studies only failed to find a significant association. Review. PMID: 25663199
    4. rs2056202 and rs2292813 in SLC25A12 may contribute significantly to autism spectrum disorders risk. PMID: 25921325
    5. Structure of the calcium bound and calcium free N- and C-terminal domains is described, elucidating the mechanism of calcium regulation. PMID: 25410934
    6. The physiological roles of AGC1, its links to calcium homeostasis, and its involvement in autism pathogenesis, are reviewed. PMID: 21691713
    7. This study found no differences in the allele, genotype, or haplotype frequencies of these two SNPs between patients and controls. PMID: 19913066
    8. Variants of the AGC1-encoding SLC25A12 gene were neither correlated with AGC activation nor associated with autism-spectrum disorders in 309 simplex and 17 multiplex families. PMID: 18607376
    9. SLC25A12 gene is linked to autism PMID: 15056512
    10. Aralar1 has a role in determining glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells PMID: 15494407
    11. These results suggest that SLC25A12 is not a major contributor to autism risk in these families. PMID: 16648338
    12. it is unlikely that the SLC25A12 polymorphisms investigated play a substantial role in conferring susceptibility to schizophrenia PMID: 17693006
    13. rs2056202 polymorphism in SLC25A12 may be associated with levels of routines and rituals in autism and related disorders PMID: 17894412
    14. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. PMID: 18180767
    15. SLC25A12 gene is associated with autism. PMID: 19360665

    顯示更多

    收起更多

  • 相關疾病：
    Epileptic encephalopathy, early infantile, 39 (EIEE39)
  • 亞細胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性：
    Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.
  • 數據庫鏈接：

    HGNC: 10982

    OMIM: 603667

    KEGG: hsa:8604

    STRING: 9606.ENSP00000388658

    UniGene: Hs.470608



主站蜘蛛池模板： 蜜臀亚洲精品国产aⅴ综合第一| 久久午夜神器| 国产人妻一区二区三区久| 久久综合亚洲鲁鲁五月天| 精品国产乱码久久久久久乱码 | 色在线亚洲视频www| 免费观看黄网站| yw尤物av无码国产在线观看| a在线亚洲男人的天堂| 曰批全过程免费视频观看软件潮喷| 国产孩cao大人xxxx| 99e热久久免费精品首页| 好吊色欧美一区二区三区视频 | 鲁一鲁av2019在线| 精品无码国产污污污免费| 三男一女吃奶添下面视频| 狠狠躁夜夜躁人人爽天天古典| 国产av国片精品有毛| 亚洲国产av一区二区三区| 国产精品久久久久不卡绿巨人| 天堂网www在线资源最新版| 国产亚洲精品第一综合麻豆| 精品人妻av一区二区三区| 在线高清亚洲精品二区| 色欲天天婬色婬香视频综合网| 精品久久久无码中文字幕| 国产精品国产三级国产aⅴ下载| 九色精品国产成人综合网站 | 四虎永久在线精品免费网站| 亚洲日韩av一区二区三区四区 | 欧美 国产 综合 欧美 视频| 精品亚洲国产成人蜜臀优播av| 天干天干啦夜天干天天爽| 亚洲乱码国产乱码精品精| 欧美亚洲偷图色综合| 在线看片免费人成视频国产片| 精品人妻va出轨中文字幕| 92久久精品一区二区| 人妻avav中文系列久久| 男女啪啪高清无遮挡免费| 日产精品一区二区|