在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC25A12 Antibody, FITC conjugated

SLC25A12 Antibody, FITC conjugated

  • 中文名稱：
    SLC25A12兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA021478LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC25A12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC25A12
  • 別名：
    SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Calcium-binding mitochondrial carrier protein Aralar1 protein (202-317AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
  • 基因功能參考文獻：
    1. Genetic variants of SLC25A12 may be associated with risks for childhood ASD. PMID: 28536923
    2. The features of AGC1 structure and function in physiology and pathology, regulation by calcium, dependency on mitochondrial membrane potential, role in cancer cells, and tissue specificity are reviewed. AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Review. PMID: 27132995
    3. Sensitivity analyses including only studies with family-based design demonstrated significant association between autism spectrum disorders and SNPs rs2292813 and rs2056202. In contrast, sensitivity analyses including case-control design studies only failed to find a significant association. Review. PMID: 25663199
    4. rs2056202 and rs2292813 in SLC25A12 may contribute significantly to autism spectrum disorders risk. PMID: 25921325
    5. Structure of the calcium bound and calcium free N- and C-terminal domains is described, elucidating the mechanism of calcium regulation. PMID: 25410934
    6. The physiological roles of AGC1, its links to calcium homeostasis, and its involvement in autism pathogenesis, are reviewed. PMID: 21691713
    7. This study found no differences in the allele, genotype, or haplotype frequencies of these two SNPs between patients and controls. PMID: 19913066
    8. Variants of the AGC1-encoding SLC25A12 gene were neither correlated with AGC activation nor associated with autism-spectrum disorders in 309 simplex and 17 multiplex families. PMID: 18607376
    9. SLC25A12 gene is linked to autism PMID: 15056512
    10. Aralar1 has a role in determining glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells PMID: 15494407
    11. These results suggest that SLC25A12 is not a major contributor to autism risk in these families. PMID: 16648338
    12. it is unlikely that the SLC25A12 polymorphisms investigated play a substantial role in conferring susceptibility to schizophrenia PMID: 17693006
    13. rs2056202 polymorphism in SLC25A12 may be associated with levels of routines and rituals in autism and related disorders PMID: 17894412
    14. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. PMID: 18180767
    15. SLC25A12 gene is associated with autism. PMID: 19360665

    顯示更多

    收起更多

  • 相關疾病：
    Epileptic encephalopathy, early infantile, 39 (EIEE39)
  • 亞細胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性：
    Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.
  • 數據庫鏈接：

    HGNC: 10982

    OMIM: 603667

    KEGG: hsa:8604

    STRING: 9606.ENSP00000388658

    UniGene: Hs.470608



主站蜘蛛池模板： 俄罗斯美女真人性做爰| 中文天堂资源在线www| 久久精品国产色蜜蜜麻豆 | 亚洲人成网网址在线看| 中文字幕日本人妻久久久免费| 亚洲国产精品无码中文字满| 欧美影视精品久久| 日韩av片无码一区二区不卡电影| 一品二品三品中文字幕| 天堂俺去俺来也www色官网| 国产精品白丝喷浆| 特级毛片a片久久久久久| 暖暖视频日本在线观看| 人妻无码一区二区三区tv| 久久亚洲欧美国产精品| 国产精品无码无片在线观看| 日韩精品a片一区二区三区妖精| 国产精品亚洲专区无码影院| 亚洲精品无码久久久久不卡| 欧美牲交a欧美牲交aⅴ免费真 | 成人av一本不卡二卡| 欧亚乱熟女一区二区在线| 国产精品人人妻人人爽| 国产69精品久久久久乱码| 夫妻免费无码v看片| 97人妻人人揉人人躁人人| 野外少妇被弄到喷水在线观看| 久久婷婷五月综合色奶水99啪 | 人妻少妇一区二区三区| 久久99青青精品免费观看| 正在播放国产剧情亂倫| 国产成人久久精品77777综合| 中国女人大白屁股ass| 69堂人成无码免费视频果冻传媒| 东京热加勒比无码少妇| 国产精品久久久久久久久久久久午衣片| 免费观看国产小粉嫩喷水| 亚洲日韩一区二区| 性生交大片免费看女人按摩摩| 日本一卡2卡三卡4卡免费网站| 亚洲国产a∨无码中文777|