在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RXFP3 Antibody

RXFP3 Antibody

  • 中文名稱：
    RXFP3兔多克隆抗體
  • 貨號：
    CSB-PA873646DSR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA873646DSR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA873646DSR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RXFP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    RXFP3; GPCR135; RLN3R1; SALPR; Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Relaxin-3 receptor 1 protein (1-80AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • 基因功能參考文獻：
    1. This study indicated that RXFP3 mainly localised in the post-acrosomal region of sperm head and neck. PMID: 29159832
    2. The role of these four INSL5 determinants in distinguishing RXFP4 from RXFP3. PMID: 27404393
    3. Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. PMID: 27498038
    4. the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 PMID: 27353281
    5. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor PMID: 24641548
    6. Glu141 and Asp145 of the RXFP3 interact with the highly conserved arginine residues of relaxin-3. PMID: 24615237
    7. demonstrate the existence of an allosteric site for modulation of RXFP3 PMID: 22347403
    8. H3 relaxin potently activates all signaling pathways coupled to RXFP3, whereas H2 relaxin is an AP-1-biased ligand relative to H3 relaxin. PMID: 20159943
    9. GPCR135 (SALPR) is the receptor for relaxin-3 PMID: 14522968
    10. Substitution of the relaxin-3 A-chain with the A-chain from insulin-like peptide 5 results in a chimeric peptide that selectively activates GPCR135 and GPCR142. PMID: 15465925
    11. functional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteins PMID: 15956730
    12. analysis of truncated human relaxin-2 and -3 (H2 and H3) relaxin peptides and their binding and cAMP activities on RXFP1, RXFP2, and RXFP3 PMID: 18434306
    13. the N-terminus and EL2 domains of RXFP3 and RXFP4 are involved in ligand binding while TM2, 3, and 5 are critical for receptor activation. PMID: 18582868
    14. Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3. PMID: 19152634

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high leve
  • 數據庫鏈接：

    HGNC: 24883

    OMIM: 609445

    KEGG: hsa:51289

    STRING: 9606.ENSP00000328708

    UniGene: Hs.170146



主站蜘蛛池模板： 国产成人a亚洲精v品无码| 亚洲愉拍自拍另类图片| 一区二三区在线 | 中国| 久久国产色av免费观看 | 国产精品无码综合区| 无码午夜福利视频1000集| 亚洲欧美日韩一区在线观看| 国产成人无码一区二区在线观看| 性人久久久久| 18禁无遮挡无码网站免费| 亚洲乱码卡一卡二卡新区仙踪木木| 国产精品 精品国内自产拍| 乌克兰少妇videos高潮| 夜夜夜高潮夜夜爽夜夜爰爰| 午夜福利影院私人爽爽| 国产成年无码久久久免费| 人妻巨大乳一二三区| 免费又黄又爽1000禁片| 国产亚洲综合网曝门系列| 综合欧美亚洲日本一区| 亚洲a∨无码国产精品久久网| 国产av无码国产av毛片| 国产女人的高潮国语对白| 婷婷久久香蕉五月综合| 被技师按摩到高潮的少妇| 久久久久久久精品成人热色戒汤唯 | 午夜无码精品国产片| 老色69久久九九精品高潮| 日本极品少妇xxxx| 欧美xxxx做受欧美69| 久久综合av色老头免费观看| 亚洲成av人片一区二区梦乃| 无码成人aaaaa毛片| 亚洲人成精品久久久久桥| 国产精品毛片av999999| 无码人妻aⅴ一区二区三区69岛| 亚洲欧美综合区丁香五月小说| 亚洲欧洲自拍拍偷精品网| 已婚少妇美妙人妻系列| 欧美mv日韩mv国产网站app| 青青青国产在线观看免费|