在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RXFP3 Antibody

RXFP3 Antibody

  • 中文名稱：
    RXFP3兔多克隆抗體
  • 貨號：
    CSB-PA886335
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA886335(RXFP3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA886335(RXFP3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA886335(RXFP3 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RXFP3; GPCR135; RLN3R1; SALPR; Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human RXFP3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • 基因功能參考文獻：
    1. This study indicated that RXFP3 mainly localised in the post-acrosomal region of sperm head and neck. PMID: 29159832
    2. The role of these four INSL5 determinants in distinguishing RXFP4 from RXFP3. PMID: 27404393
    3. Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. PMID: 27498038
    4. the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 PMID: 27353281
    5. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor PMID: 24641548
    6. Glu141 and Asp145 of the RXFP3 interact with the highly conserved arginine residues of relaxin-3. PMID: 24615237
    7. demonstrate the existence of an allosteric site for modulation of RXFP3 PMID: 22347403
    8. H3 relaxin potently activates all signaling pathways coupled to RXFP3, whereas H2 relaxin is an AP-1-biased ligand relative to H3 relaxin. PMID: 20159943
    9. GPCR135 (SALPR) is the receptor for relaxin-3 PMID: 14522968
    10. Substitution of the relaxin-3 A-chain with the A-chain from insulin-like peptide 5 results in a chimeric peptide that selectively activates GPCR135 and GPCR142. PMID: 15465925
    11. functional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteins PMID: 15956730
    12. analysis of truncated human relaxin-2 and -3 (H2 and H3) relaxin peptides and their binding and cAMP activities on RXFP1, RXFP2, and RXFP3 PMID: 18434306
    13. the N-terminus and EL2 domains of RXFP3 and RXFP4 are involved in ligand binding while TM2, 3, and 5 are critical for receptor activation. PMID: 18582868
    14. Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3. PMID: 19152634

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high leve
  • 數據庫鏈接：

    HGNC: 24883

    OMIM: 609445

    KEGG: hsa:51289

    STRING: 9606.ENSP00000328708

    UniGene: Hs.170146



主站蜘蛛池模板： 亚洲成a人片在线播放| 边啃奶头边躁狠狠躁| av无码免费一区二区三区| 亚洲色欲色欲77777小说网站| 图片区小说区激情区偷拍区| 日韩av高潮喷水在线观看| 国产极品美女高潮抽搐免费网站 | 国产成人+亚洲欧洲+综合| 精品国产污污免费网站入口 | 亚洲成h人av无码动漫无遮挡| 1000部啪啪未满十八勿入| 波多野结衣一区二区三区av免费| 人妻无码一区二区三区tv| 国产男女猛烈无遮挡免费视频网站| 欧美村妇激情内射| 亚洲熟妇中文字幕五十中出 | 东京热人妻丝袜无码av一二三区观| 成人无码a片一区二区三区免| 亚洲一区 日韩精品 中文字幕 | 亚洲精品国产精品国产自2022| 中文在线√天堂| 少妇激情一区二区三区视频小说 | 露脸叫床粗话东北少妇| 黑人与中国少妇xxxx视频| 日韩欧国产精品一区综合无码| 亚洲最大无码中文字幕| 欧美疯狂做受xxxx高潮| 国产精品亚洲аv久久| 97色成人综合网站| 国产成人无码18禁午夜福利网址| 竹菊影视欧美日韩一区二区三区四区五区| 综合亚洲另类欧美久久成人精品| 2019最新中文字幕在线观看| 尤物蜜芽国产成人精品区| 亚洲欧洲国产码专区在线观看| 无码区日韩特区永久免费系列| 在线观看无码不卡av| 少妇被爽到高潮喷水久久欧美精品| 亚洲最大av网站在线观看| 黑人大战日本人妻嗷嗷叫不卡视频| 青青草国产线观看|