在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RXFP3 Antibody

RXFP3 Antibody

  • 中文名稱：
    RXFP3兔多克隆抗體
  • 貨號：
    CSB-PA020280
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RXFP3; GPCR135; RLN3R1; SALPR; Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Relaxin Receptor 3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • 基因功能參考文獻：
    1. This study indicated that RXFP3 mainly localised in the post-acrosomal region of sperm head and neck. PMID: 29159832
    2. The role of these four INSL5 determinants in distinguishing RXFP4 from RXFP3. PMID: 27404393
    3. Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. PMID: 27498038
    4. the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 PMID: 27353281
    5. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor PMID: 24641548
    6. Glu141 and Asp145 of the RXFP3 interact with the highly conserved arginine residues of relaxin-3. PMID: 24615237
    7. demonstrate the existence of an allosteric site for modulation of RXFP3 PMID: 22347403
    8. H3 relaxin potently activates all signaling pathways coupled to RXFP3, whereas H2 relaxin is an AP-1-biased ligand relative to H3 relaxin. PMID: 20159943
    9. GPCR135 (SALPR) is the receptor for relaxin-3 PMID: 14522968
    10. Substitution of the relaxin-3 A-chain with the A-chain from insulin-like peptide 5 results in a chimeric peptide that selectively activates GPCR135 and GPCR142. PMID: 15465925
    11. functional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteins PMID: 15956730
    12. analysis of truncated human relaxin-2 and -3 (H2 and H3) relaxin peptides and their binding and cAMP activities on RXFP1, RXFP2, and RXFP3 PMID: 18434306
    13. the N-terminus and EL2 domains of RXFP3 and RXFP4 are involved in ligand binding while TM2, 3, and 5 are critical for receptor activation. PMID: 18582868
    14. Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3. PMID: 19152634

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high leve
  • 數據庫鏈接：

    HGNC: 24883

    OMIM: 609445

    KEGG: hsa:51289

    STRING: 9606.ENSP00000328708

    UniGene: Hs.170146



主站蜘蛛池模板： 午夜福利免费0948视频| 88国产精品欧美一区二区三区| 欧美日韩免费专区在线| 日韩在线一区二区不卡视频| 国产午夜a理论毛片| 日韩人妻无码一区二区三区俄罗斯| 精品国产乱码久久久久久婷婷| 粗了大了 整进去好爽视频| 欧亚精品一区三区免费| 国产免费人成网站x8x8| 2021国产成人精品久久| 国产精品一久久香蕉国产线看观看 | 男女后进式猛烈xx00动态图片| 天堂一区人妻无码| 人人妻人人爽人人做夜欢视频九色| 麻花豆传媒剧国产免费mv观看| 国产精品综合色区在线观看| 亚洲欧洲美洲无码精品va| 亚洲欧洲自偷自拍图片| 乱码国产丰满人妻www| 色www视频永久免费| 久久婷婷五月综合色精品| 老司机免费的精品视频| 国产乱子伦一区二区三区四区五区 | 女人扒下裤让男人桶到爽| 亚洲国产美女久久久久| 国产精品无码专区| 久久亚洲一区二区三区四区五区| √最新版天堂资源网在线| 亚洲综合色婷婷七月丁香| 欧美人与动牲交免费观看网| 一区一区三区产品乱码| 粗了大了 整进去好爽视频| 中文天堂最新版在线www| 国内自拍久久久久影院| 欧美牲交a欧牲交aⅴ久久| 国产成人精品综合久久久久| 色欲人妻aaaaaa无码| 亚洲男人的天堂一区二区| 亚洲综合另类小说色区一| 亚洲中文字幕精品久久|