在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RXFP3 Antibody

RXFP3 Antibody

  • 中文名稱：
    RXFP3兔多克隆抗體
  • 貨號：
    CSB-PA873646DSR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: RXFP3 antibody at 3.68µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 51 kDa
      Observed band size: 51 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA873646DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA873646DSR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RXFP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    RXFP3; GPCR135; RLN3R1; SALPR; Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Relaxin-3 receptor 1 protein (1-80AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • 基因功能參考文獻：
    1. This study indicated that RXFP3 mainly localised in the post-acrosomal region of sperm head and neck. PMID: 29159832
    2. The role of these four INSL5 determinants in distinguishing RXFP4 from RXFP3. PMID: 27404393
    3. Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. PMID: 27498038
    4. the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 PMID: 27353281
    5. we demonstrated distinct patterns of signalling for H3 and H2 relaxin and R3(BDelta23-27)R/I5 at the RXFP3 receptor PMID: 24641548
    6. Glu141 and Asp145 of the RXFP3 interact with the highly conserved arginine residues of relaxin-3. PMID: 24615237
    7. demonstrate the existence of an allosteric site for modulation of RXFP3 PMID: 22347403
    8. H3 relaxin potently activates all signaling pathways coupled to RXFP3, whereas H2 relaxin is an AP-1-biased ligand relative to H3 relaxin. PMID: 20159943
    9. GPCR135 (SALPR) is the receptor for relaxin-3 PMID: 14522968
    10. Substitution of the relaxin-3 A-chain with the A-chain from insulin-like peptide 5 results in a chimeric peptide that selectively activates GPCR135 and GPCR142. PMID: 15465925
    11. functional response to H3 relaxin and other relaxin/insulin peptides of GPCR135 expressed in CHO-K1 cells was measured in the cytosensor microphysiometer and analyzed using inhibitors of signal transduction proteins PMID: 15956730
    12. analysis of truncated human relaxin-2 and -3 (H2 and H3) relaxin peptides and their binding and cAMP activities on RXFP1, RXFP2, and RXFP3 PMID: 18434306
    13. the N-terminus and EL2 domains of RXFP3 and RXFP4 are involved in ligand binding while TM2, 3, and 5 are critical for receptor activation. PMID: 18582868
    14. Results decribe the structural and functional aspects of the interaction between relaxin-3 and its receptor, RXFP3. PMID: 19152634

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high leve
  • 數據庫鏈接：

    HGNC: 24883

    OMIM: 609445

    KEGG: hsa:51289

    STRING: 9606.ENSP00000328708

    UniGene: Hs.170146



主站蜘蛛池模板： 97精品国自产在线偷拍| 97人人超碰国产精品最新| 久久精品人人槡人妻人人玩av| 乌克兰性欧美精品高清| 亚洲 欧美 国产 动漫 综合| 精品无码av无码免费专区| 无码精品人妻一区二区三区影院 | 国产伦精品一区二区三区免费迷 | 亚洲国产制服丝袜高清在线| 国产老熟妇精品观看| www一区二区www免费| 高潮又爽又无遮挡又免费| 久久综合色一综合色88| 久久se精品一区二区三区| 人人爽人人爽人人片av亚洲 | 99e热久久免费精品首页| 一区二区在线 | 欧洲| 久久久性色精品国产免费观看 | 五月婷六月婷婷俺也去| 熟女chachacha性少妇| 亚洲人成伊人成综合网久久久| 高潮毛片又色又爽免费| 日躁夜躁狠狠躁2001| 午夜福利影院私人爽爽| 色视频综合无码一区二区三区| 国产伦精品一区二区三区免.费| 西欧free性满足hd老熟妇| 人与禽交av在线播放| 亚洲欧洲日产韩国无码| 国产成人精品日本亚洲语音| 国产在线国偷精品产拍| 一二三四在线观看免费视频| 香蕉欧美成人精品a∨在线观看 | 欧洲国产伦久久久久久久| 无尺码精品产品视频| 麻豆果冻精东九一传媒mv| 午夜一区二区亚洲福利| 最近免费中文字幕mv在线视频3| 国产福利精品一区二区| 国产沙发午睡系列999| 99热精国产这里只有精品|