在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Phospho-HIST1H1E (T145) Antibody

Phospho-HIST1H1E (T145) Antibody

  • 中文名稱：
    磷酸化-HIST1H1E (T145)兔多克隆抗體
  • 貨號：
    CSB-PA010380OA145phHU
  • 規(guī)格：
    ￥660
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA010380OA145phHU at 1:7.5, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Peptide sequence around site of Phospho-Thr (145) derived from Human Histone H1.4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:1-1:10
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 男女啪祼交视频| 欧美日韩亚洲中文字幕一区二区三区| 亚洲 欧美 变态 另类 综合| 国产久热精品无码激情| 国产成人精品免费视频大全五级 | 狠狠色婷婷久久综合频道日韩| 国产精品亚洲精品一区二区| 成人免费午夜无码视频| 无码毛片内射白浆视频| 国产亚洲美女精品久久久| 国产aⅴ精品一区二区三区久久| 顶级欧美做受xxx000| 国产成人无码区免费网站| 午夜精品久久久内射近拍高清| 中文字幕无码专区人妻系列| 天堂中文在线最新版地址 | 欧美 亚洲 国产 制服 中文| 日韩人妻无码一区二区三区俄罗斯| 国产精品国产高清国产av| 色情无码一区二区三区| 久久精品99无色码中文字幕| 五月综合激情婷婷六月色窝| 丰满人妻熟妇乱又伦精品软件| 欧洲日韩亚洲无线在码| 国内精品视频一区二区八戒| 亚洲熟妇中文字幕五十中出 | 亚洲欧美日韩二三区在线| 中文字幕 乱码 中文乱码视频| 日本护士毛茸茸| 日韩 无码 偷拍 中文字幕| 国产精品夜夜春夜夜爽久久| 日本va在线视频播放| 久久精品人妻少妇一区二区三区| 国产白嫩护士在线播放| 免费国产午夜视频在线| 99久久国产热无码精品免费| 久热这里只精品99国产6-99re视…| av无码中出一区二区三区| 东京热无码av一区二区| 人人澡人摸人人添| 区二区三区国产精华液区别大吗 |