在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Phospho-HIST1H1E (T145) Antibody

Phospho-HIST1H1E (T145) Antibody

  • 中文名稱：
    磷酸化-HIST1H1E (T145)兔多克隆抗體
  • 貨號：
    CSB-PA010380OA145phHU
  • 規(guī)格：
    ￥660
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA010380OA145phHU at 1:7.5, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Peptide sequence around site of Phospho-Thr (145) derived from Human Histone H1.4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:1-1:10
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 在线资源天堂www| 精品国产成人高清在线观看| 亚洲精品久久一区二区无卡| 国产男女猛烈视频在线观看| 国产放荡对白视频在线观看| 亚洲老熟女与小伙bbwtv| 人禽伦免费交视频播放| 忍不住的亲子中文字幕| 国产性夜夜春夜夜爽1a片| 国产一区二区无码蜜芽精品| 亚洲性色成人av| 国产精品毛片在线完整版sab| 欧美多毛肥胖老妇做爰| 乱子伦一区二区三区| aaaaa少妇高潮大片| 中文字幕在线亚洲二区| 亚洲乱码卡一卡二卡新区仙踪木木 | 国产精品免费观看调教网| 亚洲欧美日韩另类丝袜一区| 日韩成人大屁股内射喷水| 性色av蜜臀av色欲av| 色综合色狠狠天天综合色| 无码少妇一区二区浪潮免费| 成年女人片免费视频播放a| av小次郎收藏| 无码不卡av东京热毛片| 国产伦精品一区二区三区妓女下载| 夜夜躁狠狠躁日日躁202| 中文字幕无码中文字幕有码a| 亚洲乱码一区av春药高潮| 吃奶呻吟打开双腿做受动态图 | 色94色欧美sute亚洲线路一| 波多野结衣乳巨码无在线| 中文字幕人妻中文av不卡专区 | 精品无码久久久久国产动漫3d| 中文乱码字幕高清一区二区| 亚洲性夜色噜噜噜在线观看不卡| 亚洲小说春色综合另类| 亚洲国产aⅴ成人精品无吗| 中国熟妇牲交视频免费| 亚洲精品午夜一区人人爽|