在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Phospho-HIST1H1E (S35) Antibody

  • 中文名稱:
    磷酸化-HIST1H1E (S35)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA35phHU
  • 規格:
    ¥660
  • 圖片:
    • Immunocytochemistry analysis of Hela cells using CSB-PA010380PA35phHU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA010380PA35phHU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Phospho-Ser (35) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, ICC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    ICC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 美女粉嫩饱满的一线天mp4| 99精品国产在热久久无码| 亚洲va无码va在线va天堂| 最新69成人精品视频免费| 中文字幕无线观看中文字幕| 国产乱色精品成人免费视频| 无码专区天天躁天天躁在线| 国产成人剧情av麻豆果冻| 亚洲精品无码av中文字幕| 无码人妻av一区二区三区蜜臀| 欧美日韩一区二区三区自拍| 国产精品夜夜春夜夜爽久久| 亚洲精品久久久久久久蜜桃臀| 亚洲精品一区二区三区四区五区| 自拍偷在线精品自拍偷99| 精品国内自产拍在线观看| 中文字幕精品一二三四五六七八| 无码人妻av一二区二区三区| 最新系列国产专区|亚洲国产| 青青久久成人免费影院| 狠狠色狠狠色综合网| 国产午夜无码精品免费看| 亚洲中文字幕av不卡无码| 成人亚洲精品777777| 最新高清无码专区| 中文人妻无码一区二区三区| av无码av无码专区| 亚洲欧美日韩中文在线制服| 波多野吉衣av无码| 秋霞鲁丝片av无码| 欧美饥渴少妇xxxxx性| 国产精品区免费视频| 男女超爽视频免费播放| 亚洲熟妇av一区二区三区宅男| 午夜不卡无码中文字幕影院| 精品少妇人妻av一区二区| 国产亚洲精品福利在线无卡一 | 国产精品亚洲a∨天堂不卡| 亚洲人成在线影院| 久久婷婷综合激情亚洲狠狠| 日韩欧美国产一区精品|