在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Mono-methyl-HIST1H1E (K63) Antibody

Mono-methyl-HIST1H1E (K63) Antibody

  • 中文名稱：
    Mono-methyl-HIST1H1E (K63)兔多克隆抗體
  • 貨號(hào)：
    CSB-PA010380OA63me1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunocytochemistry analysis of CSB-PA010380OA63me1HU diluted at 1:30 and staining in Hela cells performed on a Leica BondTM system. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human Histone H1.4 protein (57-69aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    ICC 1:10-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻(xiàn)：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Rahman syndrome (RMNS)
  • 亞細(xì)胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 人妻少妇精品无码专区| 女人下面毛多水多视频| 永久免费的无码中文字幕| 国内精品视频自在一区| 亚洲成av人片在线观看天堂无| 久久www成人影院| 曰批视频免费30分钟成人| 东京无码熟妇人妻av在线网址| 7777精品伊人久久久大香线蕉| 18禁黄无遮挡网站免费| 日韩经典精品无码一区| 久久无码喷吹高潮播放不卡 | 亚欧日韩欧美网站在线看 | 亚洲中文字幕无码永久在线 | 日韩精品久久久肉伦网站| 亚洲精品成人网线在线播放va | 亚洲欧美偷国产日韩| 综合 欧美 小说 另类 图| 午夜dv内射一区二区| 精品欧洲av无码一区二区| 精品国产精品久久一区免费式| 无翼乌工口全彩肉肉无遮挡18| 亚洲欧美成αⅴ人在线观看| 色视频www在线播放国产人成| 精品人伦一区二区三区蜜桃免费| 免费无码av片在线观看| 成人爽a毛片免费看| 人妻三级日本三级日本三级极| 人妻巨大乳hd免费看| 国产精品免费一区二区三区四区| 亚洲色无码国产精品网站可下载| 欧洲精品一卡2卡三卡4卡影视| 亚洲综合日韩av无码毛片| 欧美日韩在线亚洲综合国产人| 成人性生交大片免费看| 天天澡日日澡狠狠欧美老妇| 人妻无码熟妇乱又伦精品视频| 色偷偷色噜噜狠狠网站久久 | 亚洲а∨天堂久久精品| 夜夜高潮夜夜爽夜夜爱爱一区 | 天堂va蜜桃一区二区三区|