在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Mono-methyl-HIST1H1E (K25) Antibody

Mono-methyl-HIST1H1E (K25) Antibody

  • 中文名稱：
    Mono-methyl-HIST1H1E (K25)兔多克隆抗體
  • 貨號：
    CSB-PA010380OA25me1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunocytochemistry analysis of CSB-PA010380OA25me1HU diluted at 1:20 and staining in Hela cells performed on a Leica BondTM system. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human Histone H1.4 protein (21-33aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    ICC 1:10-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻(xiàn)：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Rahman syndrome (RMNS)
  • 亞細(xì)胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 精品无码国产自产拍在线观看| 国产欧美高清在线观看| 午夜熟女插插xx免费视频| 狠狠色综合网久久久久久| 亚洲高清乱码午夜电影网| 国内精品视频自在一区| 人人做人人爽久久久精品| 欧美亚洲另类自拍丝袜| 国产全肉乱妇杂乱视频| 少妇被粗大猛进进出出s小说| 十八岁污网站在线观看| 精品乱码无人区一区二区| 三级无码在钱av无码在钱| 国产成人无码午夜视频在线播放| 免费又黄又硬又爽大片| 极品少妇hdxx麻豆hdxx| 中文字幕乱码一区二区三区免费| 国产亚洲精aa在线观看see| 久久97超碰色中文字幕总站 | 中文人妻熟女乱又乱精品| 国产精品久久久久久久久人妻 | 日韩不卡1卡2卡三卡网站| 久久久精品日本一区二区三区| 久久www免费人成精品| 好了av四色综合无码久久| 九九视频麻婆豆腐在线观看| 军人粗大的内捧猛烈进出视频| 波多野结衣在线精品视频| 久久综合一色综合久久小蛇| 新版天堂8中文在线最新版官网 | 免费观看国产小粉嫩喷水 | 窝窝午夜色视频国产精品破| 欧美亚洲精品中文字幕乱码| 欧美嫩交一区二区三区| 在线播放国产麻豆va剧情| 日本熟妇人妻xxxx| 日本肉体xxxx裸体137大胆| 人人妻人人爽人人澡av| 男人边吃奶边揉好爽免费视频| 亚洲精品乱码久久久久久日本| 国产艳妇av在线出轨|