在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Mono-methyl-HIST1H1E (K147) Antibody

  • 中文名稱:
    Mono-methyl-HIST1H1E (K147)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA147me1HU
  • 規格:
    ¥660
  • 圖片:
    • Immunocytochemistry analysis of MCF-7 cells using CSB-PA010380PA147me1HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA010380PA147me1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Mono-methyl-Lys (147) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, ICC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    ICC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 亚洲日韩欧美国产高清αv| 亚洲一区二区三区自拍天堂| 久久人人爽爽人人爽人人片av| 可以直接免费观看的av网站| 国产人妻黑人一区二区三区| 免费看国产精品3a黄的视频| 成 人影片 aⅴ毛片免费观看 | 国产口爆吞精在线视频2020版| 人妻丰满熟妇av无码区hd| 天堂网www在线资源最新版| 丰满少妇高潮惨叫久久久| 特级做a爰片毛片免费看无码| 人妻系列无码专区久久五月天| 18禁男女污污污午夜网站免费暖暖| 久久精品aⅴ无码中文字字幕| 欧美s码亚洲码精品m码| 乱码人妻一区二区三区| 日韩内射美女片在线观看网站| 久久精品水蜜桃av综合天堂| 学生妹亚洲一区二区| 国产亚洲中文日本不卡二区| 亚洲国产欧美在线观看片不卡| 人妻熟女一区二区aⅴ千叶宁真| 黑人巨茎大战俄罗斯美女| 精品午夜国产福利观看| 亚洲精品国产av成拍色拍婷婷| 蜜臀av在线播放| 亚洲国产精品无码久久青草| 国产成人免费高清直播| av午夜福利一片免费看久久| 成人精品一区二区三区中文字幕| 日韩av爽爽爽久久久久久| 国产福利免费视频不卡| 无码中文字幕在线播放2| 亚洲日韩看片无码电影| 天堂资源在线www在线观看| 国产中文字字幕乱码无限| 成人做爰100部片免费下载| 亚洲高清国产拍精品26u| 成年女人免费碰碰视频| 在线看片免费人成视频福利 |