在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MMP19 Antibody

  • 中文名稱:
    MMP19兔多克隆抗體
  • 貨號:
    CSB-PA857450ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA857450ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human bladder cancer using CSB-PA857450ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MMP19 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Matrix metalloproteinase 18 antibody; Matrix metalloproteinase 19 isoform rasi1 antibody; Matrix metalloproteinase 19 isoform rasi9 antibody; Matrix metalloproteinase RASI antibody; Matrix metalloproteinase-18 antibody; Matrix metalloproteinase-19 antibody; MMP-18 antibody; MMP-19 antibody; MMP18 antibody; MMP19 antibody; MMP19_HUMAN antibody; Preproprotein matrix metalloproteinase 19 isoform rasi6 antibody; RASI 1 antibody; RASI1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Matrix metalloproteinase-19 protein (209-508AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
  • 基因功能參考文獻:
    1. Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). PMID: 26692439
    2. transcriptional target of ligand-bound activated estrogen receptor beta acting on a specificity protein-1 binding site PMID: 26700939
    3. the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness. PMID: 26548962
    4. Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells. PMID: 26292259
    5. Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly. PMID: 25581579
    6. the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. PMID: 25840998
    7. The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed. PMID: 25056434
    8. Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC PMID: 25250855
    9. ASNS and MMP19, along with eIF3a, are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma. PMID: 23956056
    10. Up-regulation of matrix metalloproteinase-19 (MMP19) induced by lung injury may play a protective role in the development of fibrosis through the induction of prostaglandin-endoperoxide synthase 2 (PTGS2). PMID: 22859522
    11. MMP-19 processes human plasminogen in a characteristic cleavage pattern to generate three angiostatin-like fragments PMID: 21787393
    12. vascular MMP-19 expression significantly associated with Cerebral amyloid angiopathy--associated intracerebral haemorrhage PMID: 21261556
    13. the increase of MMP19 expression hallmarks the progression of cutaneous melanoma PMID: 20098411
    14. Taken together, these results indicate that MMP19 is highly expressed in proliferating astrocytoma/glioma cells, and that its expression may facilitate their invasion through brain extracellular matrix components. PMID: 20142769
    15. MMP-19 is expressed by myeloid cells in an adhesion-dependent manner and associates with the cell surface by an interaction with the hemopexin-like domain. PMID: 11801661
    16. Downregulation of MMP-19 expression in the epidermis is associated with transformation and histologic dedifferentiation in skin neoplasms PMID: 12516088
    17. MMP-19 is a likely candidate to be the major IGFBP-3 degrading MMP PMID: 12937269
    18. the importance of MMP19 as a predictor of secondary Extramammary Paget's disease or the putative origin of Paget's cells from the dermal adenocarcinoma cells of apocrine duct origin PMID: 15239678
    19. MMP-19 actively participates in the early stages of SCC invasion. PMID: 15868410
    20. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
    21. MMP-19 may have a role in tumor invasiveness in patients with oropharyngeal squamous cell carcinoma PMID: 18161657

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Cavitary optic disc anomalies (CODA)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Peptidase M10A family
  • 組織特異性:
    Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and r
  • 數據庫鏈接:

    HGNC: 7165

    OMIM: 601807

    KEGG: hsa:4327

    STRING: 9606.ENSP00000313437

    UniGene: Hs.591033



主站蜘蛛池模板: 伊人久久大香线蕉亚洲| 精品久久久无码中文字幕| 人妻少妇精品视频二区| 日韩人妻无码一区二区三区久久99 | 国产日韩av免费无码一区二区三区 | 国产精品自产拍在线观看| 国产精久久一区二区三区| 中国精品无码免费专区午夜 | 欧美欧洲成本大片免费| 精品国产精品国产偷麻豆| 欧美牲交a欧美牲交aⅴ图片| 亚洲精品久久yy5099| 国产av午夜精品一区二区三| 无码av免费一区二区三区| 色一情一区二| 99久久国产综合精品swag| 久久久久国产精品人妻aⅴ牛牛 | 日本三级带日本三级带黄| 欧美日本韩国亚洲| 欧美一夜爽爽爽爽爽爽| 国产破外女出血视频| 黑人巨大av在线播放无码| 国产亚州精品女人久久久久久 | 午夜性开放午夜性爽爽| 午夜内射中出视频| 中文字幕人妻丝袜二区| 日韩综合无码一区二区| 国产午夜精品一区二区三区老 | 成人爽a毛片免费看| 日韩国产综合精选| 女人被狂躁的高潮免费视频| 鲁一鲁一鲁一鲁一澡| 美女裸奶100%无遮挡免费网站| 日韩在线成年视频人网站观看| 伦埋琪琪电影院久久| 98色婷婷在线| 欧美成人aa大片| 99噜噜噜在线播放| 欧美亚洲综合成人a∨在线 | 欧美3p两根一起进高清视频| 国产乱人伦av在线无码|