在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MMP19 Antibody

  • 中文名稱:
    MMP19兔多克隆抗體
  • 貨號:
    CSB-PA197483
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HuvEc cells, using MMP-19 antibody.
    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-19 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MMP19 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from Human MMP-19.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
  • 基因功能參考文獻:
    1. Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). PMID: 26692439
    2. transcriptional target of ligand-bound activated estrogen receptor beta acting on a specificity protein-1 binding site PMID: 26700939
    3. the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness. PMID: 26548962
    4. Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells. PMID: 26292259
    5. Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly. PMID: 25581579
    6. the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. PMID: 25840998
    7. The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed. PMID: 25056434
    8. Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC PMID: 25250855
    9. ASNS and MMP19, along with eIF3a, are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma. PMID: 23956056
    10. Up-regulation of matrix metalloproteinase-19 (MMP19) induced by lung injury may play a protective role in the development of fibrosis through the induction of prostaglandin-endoperoxide synthase 2 (PTGS2). PMID: 22859522
    11. MMP-19 processes human plasminogen in a characteristic cleavage pattern to generate three angiostatin-like fragments PMID: 21787393
    12. vascular MMP-19 expression significantly associated with Cerebral amyloid angiopathy--associated intracerebral haemorrhage PMID: 21261556
    13. the increase of MMP19 expression hallmarks the progression of cutaneous melanoma PMID: 20098411
    14. Taken together, these results indicate that MMP19 is highly expressed in proliferating astrocytoma/glioma cells, and that its expression may facilitate their invasion through brain extracellular matrix components. PMID: 20142769
    15. MMP-19 is expressed by myeloid cells in an adhesion-dependent manner and associates with the cell surface by an interaction with the hemopexin-like domain. PMID: 11801661
    16. Downregulation of MMP-19 expression in the epidermis is associated with transformation and histologic dedifferentiation in skin neoplasms PMID: 12516088
    17. MMP-19 is a likely candidate to be the major IGFBP-3 degrading MMP PMID: 12937269
    18. the importance of MMP19 as a predictor of secondary Extramammary Paget's disease or the putative origin of Paget's cells from the dermal adenocarcinoma cells of apocrine duct origin PMID: 15239678
    19. MMP-19 actively participates in the early stages of SCC invasion. PMID: 15868410
    20. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
    21. MMP-19 may have a role in tumor invasiveness in patients with oropharyngeal squamous cell carcinoma PMID: 18161657

    顯示更多

    收起更多

  • 相關疾病:
    Cavitary optic disc anomalies (CODA)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Peptidase M10A family
  • 組織特異性:
    Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and r
  • 數(shù)據(jù)庫鏈接:

    HGNC: 7165

    OMIM: 601807

    KEGG: hsa:4327

    STRING: 9606.ENSP00000313437

    UniGene: Hs.591033



主站蜘蛛池模板: 护士被强女千到高潮视频 | 国产高清在线精品二区| 欧美多毛肥胖老妇做爰| 情侣黄网站免费看| av片在线观看免费| 精品无人区一区二区三区在线| 天天燥日日燥| 女人被躁到高潮免费视频| 奇米777狠狠色噜噜狠狠狠| 亚洲色无码中文字幕在线| 中国免费看的片| 人妻丰满熟妇av无码区乱| 无尺码精品产品日韩| 天天综合亚洲色在线精品| 国产a线视频播放| 97国产一区二区三区四区久久 | 亚洲精品nv久久久久久久久久 | 少妇mm被擦出白浆液视频| 天天鲁在视频在线观看| 日本一卡2卡3卡四卡精品网站| 天天做天天摸天天爽天天爱| 日本高清www午色夜com| 天天爽天天摸天天碰| 欧产日产国产精品| 国产一国产aa毛片| 亚洲成av人无码综合在线观看| 国产av精国产传媒| 精品高朝久久久久9999| 别揉我奶头~嗯~啊~一区二区三区| 亚洲男人最新版本天堂| 中国大陆高清aⅴ毛片| 色综合天天综合网中文| 精品人妻系列无码专区| 国产香蕉尹人在线观看视频| 亚洲精华国产精华精华液网站| 精品国产综合区久久久久久| 非洲黑人性xxxx精品| 欧美性受xxxxzooz乱毛| 国产麻豆一精品一av一免费| 怡春院国产精品视频| 国产精品久久人妻互换|