在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MMP19 Antibody

  • 中文名稱:
    MMP19兔多克隆抗體
  • 貨號:
    CSB-PA091551
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA091551(MMP19 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA091551(MMP19 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Matrix metalloproteinase 18 antibody; Matrix metalloproteinase 19 isoform rasi1 antibody; Matrix metalloproteinase 19 isoform rasi9 antibody; Matrix metalloproteinase RASI antibody; Matrix metalloproteinase-18 antibody; Matrix metalloproteinase-19 antibody; MMP-18 antibody; MMP-19 antibody; MMP18 antibody; MMP19 antibody; MMP19_HUMAN antibody; Preproprotein matrix metalloproteinase 19 isoform rasi6 antibody; RASI 1 antibody; RASI1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human MMP19
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:15-1:50
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
  • 基因功能參考文獻:
    1. Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). PMID: 26692439
    2. transcriptional target of ligand-bound activated estrogen receptor beta acting on a specificity protein-1 binding site PMID: 26700939
    3. the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness. PMID: 26548962
    4. Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells. PMID: 26292259
    5. Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly. PMID: 25581579
    6. the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. PMID: 25840998
    7. The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed. PMID: 25056434
    8. Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC PMID: 25250855
    9. ASNS and MMP19, along with eIF3a, are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma. PMID: 23956056
    10. Up-regulation of matrix metalloproteinase-19 (MMP19) induced by lung injury may play a protective role in the development of fibrosis through the induction of prostaglandin-endoperoxide synthase 2 (PTGS2). PMID: 22859522
    11. MMP-19 processes human plasminogen in a characteristic cleavage pattern to generate three angiostatin-like fragments PMID: 21787393
    12. vascular MMP-19 expression significantly associated with Cerebral amyloid angiopathy--associated intracerebral haemorrhage PMID: 21261556
    13. the increase of MMP19 expression hallmarks the progression of cutaneous melanoma PMID: 20098411
    14. Taken together, these results indicate that MMP19 is highly expressed in proliferating astrocytoma/glioma cells, and that its expression may facilitate their invasion through brain extracellular matrix components. PMID: 20142769
    15. MMP-19 is expressed by myeloid cells in an adhesion-dependent manner and associates with the cell surface by an interaction with the hemopexin-like domain. PMID: 11801661
    16. Downregulation of MMP-19 expression in the epidermis is associated with transformation and histologic dedifferentiation in skin neoplasms PMID: 12516088
    17. MMP-19 is a likely candidate to be the major IGFBP-3 degrading MMP PMID: 12937269
    18. the importance of MMP19 as a predictor of secondary Extramammary Paget's disease or the putative origin of Paget's cells from the dermal adenocarcinoma cells of apocrine duct origin PMID: 15239678
    19. MMP-19 actively participates in the early stages of SCC invasion. PMID: 15868410
    20. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
    21. MMP-19 may have a role in tumor invasiveness in patients with oropharyngeal squamous cell carcinoma PMID: 18161657

    顯示更多

    收起更多

  • 相關疾病:
    Cavitary optic disc anomalies (CODA)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Peptidase M10A family
  • 組織特異性:
    Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and r
  • 數據庫鏈接:

    HGNC: 7165

    OMIM: 601807

    KEGG: hsa:4327

    STRING: 9606.ENSP00000313437

    UniGene: Hs.591033



主站蜘蛛池模板: 51久久国产露脸精品国产| 成人黄网站高清免费视频| 大香线蕉伊人精品超碰| 国产情侣大量精品视频| 又黄又湿免费高清视频| 亚洲乱色熟女一区二区三区丝袜| 鲁死你av资源站| 国产精品亚洲一区二区三区在线| 国产亚洲色婷婷久久99精品| 97成人碰碰久久人人超级碰oo| 亚洲中文字幕av每天更新| 少妇无码av无码专线区大牛影院| 男人添女人囗交做爰视频 | 亚洲国产精品无码久久98| 精品久久久久久无码人妻| 高清粉嫩无套内谢国语播放| 久久久噜噜噜久久熟女色| 欧美黑人xxxx性高清版| 76少妇精品导航| 日本不卡高字幕在线2019| 国产拍拍拍无码视频免费| 美女视频黄的全免费视频网站| 深夜国产成人福利在线观看| 欧美老妇人与禽交| 寂寞少妇做spa按摩无码| 中文字幕日产熟女乱码| 精品亚洲成av人在线观看| 国产女主播喷水视频在线观看| 亚洲色大成网站www永久网站| 亚洲欧美日韩在线码| 天堂在线最新版www中文| 国产成人一区二区三区app| 日本一本二本三区免费| 人人妻人人澡人人爽国产| 米奇影院888奇米色99在线| 久久人人爽人人爽人人片av不 | 亚洲精品成人av在线| av免费不卡国产观看| 国自产拍偷拍精品啪啪模特 | 日韩国产精品人妻无码久久久| 国产精品无码天天爽视频|