在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Matrix metalloproteinase-19 (MMP19)

Recombinant Human Matrix metalloproteinase-19 (MMP19)

  • 中文名稱：
    人MMP19重組蛋白
  • 貨號：
    CSB-YP857450HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人MMP19重組蛋白
  • 貨號：
    CSB-EP857450HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人MMP19重組蛋白
  • 貨號：
    CSB-EP857450HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人MMP19重組蛋白
  • 貨號：
    CSB-BP857450HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人MMP19重組蛋白
  • 貨號：
    CSB-MP857450HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Matrix metalloproteinase 18 ; Matrix metalloproteinase 19 isoform rasi1; Matrix metalloproteinase 19 isoform rasi9; Matrix metalloproteinase RASI; Matrix metalloproteinase-18; Matrix metalloproteinase-19; MMP-18; MMP-19; MMP18; MMP19; MMP19_HUMAN; Preproprotein matrix metalloproteinase 19 isoform rasi6; RASI 1; RASI1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    98-508
  • 氨基酸序列
    YLL LGRWRKKHLT FRILNLPSTL PPHTARAALR QAFQDWSNVA PLTFQEVQAG AADIRLSFHG RQSSYCSNTF DGPGRVLAHA DIPELGSVHF DEDEFWTEGT YRGVNLRIIA AHEVGHALGL GHSRYSQALM APVYEGYRPH FKLHPDDVAG IQALYGKKSP VIRDEEEEET ELPTVPPVPT EPSPMPDPCS SELDAMMLGP RGKTYAFKGD YVWTVSDSGP GPLFRVSALW EGLPGNLDAA VYSPRTQWIH FFKGDKVWRY INFKMSPGFP KKLNRVEPNL DAALYWPLNQ KVFLFKGSGY WQWDELARTD FSSYPKPIKG LFTGVPNQPS AAMSWQDGRV YFFKGKVYWR LNQQLRVEKG YPRNISHNWM HCRPRTIDTT PSGGNTTPSG TGITLDTTLS ATETTFEY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
  • 基因功能參考文獻：
    1. Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). PMID: 26692439
    2. transcriptional target of ligand-bound activated estrogen receptor beta acting on a specificity protein-1 binding site PMID: 26700939
    3. the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness. PMID: 26548962
    4. Loss of NDRG2 induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells. PMID: 26292259
    5. Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly. PMID: 25581579
    6. the intima+media of IPAH vessels, collagens (COL4A5, COL14A1, and COL18A1), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 were higher expressed, whereas MMP10, ADAM17, TIMP1, and TIMP3 were less abundant. PMID: 25840998
    7. The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed. PMID: 25056434
    8. Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC PMID: 25250855
    9. ASNS and MMP19, along with eIF3a, are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma. PMID: 23956056
    10. Up-regulation of matrix metalloproteinase-19 (MMP19) induced by lung injury may play a protective role in the development of fibrosis through the induction of prostaglandin-endoperoxide synthase 2 (PTGS2). PMID: 22859522
    11. MMP-19 processes human plasminogen in a characteristic cleavage pattern to generate three angiostatin-like fragments PMID: 21787393
    12. vascular MMP-19 expression significantly associated with Cerebral amyloid angiopathy--associated intracerebral haemorrhage PMID: 21261556
    13. the increase of MMP19 expression hallmarks the progression of cutaneous melanoma PMID: 20098411
    14. Taken together, these results indicate that MMP19 is highly expressed in proliferating astrocytoma/glioma cells, and that its expression may facilitate their invasion through brain extracellular matrix components. PMID: 20142769
    15. MMP-19 is expressed by myeloid cells in an adhesion-dependent manner and associates with the cell surface by an interaction with the hemopexin-like domain. PMID: 11801661
    16. Downregulation of MMP-19 expression in the epidermis is associated with transformation and histologic dedifferentiation in skin neoplasms PMID: 12516088
    17. MMP-19 is a likely candidate to be the major IGFBP-3 degrading MMP PMID: 12937269
    18. the importance of MMP19 as a predictor of secondary Extramammary Paget's disease or the putative origin of Paget's cells from the dermal adenocarcinoma cells of apocrine duct origin PMID: 15239678
    19. MMP-19 actively participates in the early stages of SCC invasion. PMID: 15868410
    20. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
    21. MMP-19 may have a role in tumor invasiveness in patients with oropharyngeal squamous cell carcinoma PMID: 18161657

    顯示更多

    收起更多

  • 相關疾病：
    Cavitary optic disc anomalies (CODA)
  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Peptidase M10A family
  • 組織特異性：
    Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and r
  • 數據庫鏈接：

    HGNC: 7165

    OMIM: 601807

    KEGG: hsa:4327

    STRING: 9606.ENSP00000313437

    UniGene: Hs.591033



主站蜘蛛池模板： 区二区三区玖玖玖| 亚洲第一无码精品立川理惠| 国产av仑乱内谢| 国产精品无码专区久久久| 中文字幕无码精品亚洲资源网 | 三级全黄的视频在线观看| 亚欧免费无码aⅴ在线观看| 国产亚洲精品久久久久秋霞| 日韩欧无码一区二区三区免费不卡 | 女人爽到高潮潮喷18禁网站| 少妇被爽到高潮在线观看| 伊人久久大香线蕉av成人| 日本va欧美va精品发布| 99久无码中文字幕一本久道| 少妇被粗大的猛进出69影院| 男女18禁啪啪无遮挡激烈网站| 人妻中文无码久热丝袜| 久久久精品久久日韩一区综合| 少妇人妻中文字幕污| 特级毛片在线大全免费播放| 国产午夜精品一区二区三区嫩草| 亚洲大成色www永久网站动图| 亚洲人成黄网站69影院| 无码日韩精品一区二区人妻| 骚虎视频在线观看| 2018年秋霞无码片| 欧美寡妇xxxx黑人猛交| 免费看国产曰批40分钟| 无码中文字幕av免费放| 亚洲自偷自拍另类11p| 九九久久精品国产av片国产| 国产69精品久久久久久妇女迅雷| 女人19水真多免费毛片| 熟女人妻aⅴ一区二区三区60路| 日日噜噜夜夜狠狠久久丁香五月 | 在线看片国产日韩欧美亚洲| 国产男女猛烈无遮挡a片漫画| 国产成av人片在线观看天堂无码| av无码人妻中文字幕| 久久精品中文字幕一区| 日本成熟老妇乱|