在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MIB2 Antibody

MIB2 Antibody

  • 中文名稱：
    MIB2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA013803GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MIB2
  • 別名：
    MIB2 antibody; SKD antibody; ZZANK1 antibody; E3 ubiquitin-protein ligase MIB2 antibody; EC 2.3.2.27 antibody; Mind bomb homolog 2 antibody; Novel zinc finger protein antibody; Novelzin antibody; Putative NF-kappa-B-activating protein 002N antibody; RING-type E3 ubiquitin transferase MIB2 antibody; Skeletrophin antibody; Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MIB2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
  • 基因功能參考文獻(xiàn)：
    1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
    2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
    3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
    4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
    5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
    6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
    7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
    8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
  • 組織特異性：
    Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30577

    OMIM: 611141

    KEGG: hsa:142678

    STRING: 9606.ENSP00000426103

    UniGene: Hs.135805



主站蜘蛛池模板： 久久香蕉综合色一综合色88| 1000部拍拍拍18勿入免费视频下载| 丰满人妻被中出中文字幕| 日本丰满妇人成熟免费中文字幕| 国产精品久久久久不卡绿巨人| 国产妇女馒头高清泬20p多毛| 亚洲一区激情校园小说| 欧美一性一乱一交一免费视频| 福利姬国产精品一区在线| 一本大道久久久久精品嫩草| 国产亚洲精品久久久久久打不开| 日产欧美国产日韩精品| 亚洲熟妇无码av不卡在线| 最爽free性欧美人妖| 亚洲欧洲无卡二区视頻| 欧美熟妇性xxxx交潮喷| 97人妻熟女成人免费视频色戒 | 丰满女人又爽又紧又丰满| 中文字幕亚洲乱码熟女一区二区| 一本一道久久综合久久| 色噜噜狠狠色综合av| 性猛交ⅹxxx富婆视频| 最新色国产精品精品视频| 亚洲国产制服丝袜先锋| 久久精品久久久久观看99水蜜桃 | 1000部夫妻午夜免费| 国产爆乳无码一区二区麻豆| 青青草国产精品欧美成人| 亚洲欧美不卡高清在线| 少妇被爽到高潮动态图| av无码东京热亚洲男人的天堂| 日本成熟少妇喷浆视频| 亚洲国产成人久久综合区| 亚洲精品久久久www| 亚洲人成无码网站18禁10| 国产午夜高潮熟女精品av软件| 精品国产乱码久久久久久免费| 无码h肉动漫在线观看免费| 男女做爰猛烈叫床视频动态图| 亚洲精品蜜夜内射| 午夜成人爽爽爽视频在线观看|