在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MIB2 Antibody, FITC conjugated

MIB2 Antibody, FITC conjugated

  • 中文名稱：
    MIB2兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA839291LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MIB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MIB2
  • 別名：
    MIB2 antibody; SKD antibody; ZZANK1 antibody; E3 ubiquitin-protein ligase MIB2 antibody; EC 2.3.2.27 antibody; Mind bomb homolog 2 antibody; Novel zinc finger protein antibody; Novelzin antibody; Putative NF-kappa-B-activating protein 002N antibody; RING-type E3 ubiquitin transferase MIB2 antibody; Skeletrophin antibody; Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase MIB2 protein (1-128AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
  • 基因功能參考文獻：
    1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
    2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
    3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
    4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
    5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
    6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
    7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
    8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
  • 組織特異性：
    Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
  • 數據庫鏈接：

    HGNC: 30577

    OMIM: 611141

    KEGG: hsa:142678

    STRING: 9606.ENSP00000426103

    UniGene: Hs.135805



主站蜘蛛池模板： 免费久久人人爽人人爽av| 天天躁夜夜踩很很踩2022| 极品少妇被黑人白浆直流| 国产精品视频一区二区三区无码 | 久久精品无码一区二区app| 国产成人亚洲综合图区| 色天使久久综合给合久久97色| 男女高潮激烈免费观看| 西西人体www大胆高清视频| 熟妇人妻午夜寂寞影院| 偷窥 亚洲 另类 图片 熟女| 国产欧美在线亚洲一区| 极品少妇被猛的白浆直喷白浆| 猫咪www免费人成人入口| 伊人蕉久中文字幕无码专区 | 欧美性受xxxx黑人xyx性爽| 法国啄木乌av片在线播放| 狠狠色噜噜狠狠狠狠色综合久av| 人妻无码手机在线中文| 国精产品一区一区三区免费视频| 亚洲午夜未满十八勿入网站| 日韩免费无码一区二区视频| 国产在线看片免费人成视频| 最新精品国偷自产在线老年人| 丰满熟妇人妻av无码区| 一本加勒比hezyo无码资源网| 国产98色在线 | 国| 蜜臀av色欲a片无码一区| 熟妇的奶头又大又粗视频| 无码人妻久久久一区二区三区 | 性xxxx搡xxxxx搡欧美| 真人做作爱视频| 国产成人精品a∨一区二区| 国产成人精品亚洲777人妖| 精品久久久久久成人av | 国产在线精品一区在线观看| 失禁大喷潮在线播放| 无码人妻丰满熟妇啪啪7774| 日韩免费无码视频一区二区三区| 欧美日韩一区二区三区在线观看视频 | 国产亚洲日本精品无码|