在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MIB2 Antibody, FITC conjugated

MIB2 Antibody, FITC conjugated

  • 中文名稱：
    MIB2兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA839291LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MIB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MIB2
  • 別名：
    MIB2 antibody; SKD antibody; ZZANK1 antibody; E3 ubiquitin-protein ligase MIB2 antibody; EC 2.3.2.27 antibody; Mind bomb homolog 2 antibody; Novel zinc finger protein antibody; Novelzin antibody; Putative NF-kappa-B-activating protein 002N antibody; RING-type E3 ubiquitin transferase MIB2 antibody; Skeletrophin antibody; Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase MIB2 protein (1-128AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
  • 基因功能參考文獻：
    1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
    2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
    3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
    4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
    5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
    6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
    7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
    8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
  • 組織特異性：
    Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
  • 數據庫鏈接：

    HGNC: 30577

    OMIM: 611141

    KEGG: hsa:142678

    STRING: 9606.ENSP00000426103

    UniGene: Hs.135805



主站蜘蛛池模板： 在线不卡av片免费观看| 国产成人亚洲综合精品| 久久亚洲私人国产精品| 中国精品偷拍区偷拍无码| 国产成人av区一区二区三| 国产亚洲精品资源在线26u| 337p大胆啪啪私拍人体| 女人色极品影院| 人妻无码一区二区三区tv| 欧美精品亚洲精品日韩专区| 日韩中文亚洲欧美视频二| 久久久久九九精品影院| 另类 专区 欧美 制服| 亚洲精品无码久久久久yw| 最新精品国偷自产在线老年人| 极品美女扒开粉嫩小泬| 美女国产毛片a区内射| 亚洲大乳高潮日本专区| 亚洲综合电影小说图片区| 超清中文乱码一区| 欧美黑人又粗又大又爽免费| 国产成人亚洲精品| 免费的av网站在线观看国产精品| 日本xxx在线观看免费播放 | 日韩国产人妻一区二区三区| 久久人妻无码一区二区| 免费无码成人av电影在线播放| 极品少妇一区二区三区四区| 午夜精品久久久久久久| 亚洲中文无码a∨在线观看| 2018高清日本一道国产-在| 无码大潮喷水在线观看| 色偷偷亚洲男人本色 | av无码人妻无码男人的天堂| 久久精品中文字幕有码| 亚洲人成在线影院| 黑人巨茎大战欧美白妇免费| 三级无码在钱av无码在钱| 天天综合网天天综合色| 亚洲日韩国产一区二区三区| 国产日韩在线视看高清视频手机|