在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MIB2 Antibody, HRP conjugated

  • 中文名稱:
    MIB2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA839291LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MIB2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MIB2
  • 別名:
    MIB2 antibody; SKD antibody; ZZANK1 antibody; E3 ubiquitin-protein ligase MIB2 antibody; EC 2.3.2.27 antibody; Mind bomb homolog 2 antibody; Novel zinc finger protein antibody; Novelzin antibody; Putative NF-kappa-B-activating protein 002N antibody; RING-type E3 ubiquitin transferase MIB2 antibody; Skeletrophin antibody; Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase MIB2 protein (1-128AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
  • 基因功能參考文獻:
    1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
    2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
    3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
    4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
    5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
    6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
    7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
    8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
  • 組織特異性:
    Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
  • 數據庫鏈接:

    HGNC: 30577

    OMIM: 611141

    KEGG: hsa:142678

    STRING: 9606.ENSP00000426103

    UniGene: Hs.135805



主站蜘蛛池模板: 99亚洲男女激情在线观看| 亚洲人成网站18禁止中文字幕| 精品一区二区av天堂| 乱妇乱女熟妇熟女网站| 韩国三级在线观看久| 日韩内射激情视频在线播放免费 | 国产精品美女乱子伦高潮| 无码人妻一区二区三区av | 国产成人夜色高潮福利影视| 国产精品99久久99久久久动漫| 久久亚洲私人国产精品| 久久综合九色综合97伊人| 最新无码a∨在线观看| 屁屁影院ccyy备用地址| 少妇高潮灌满白浆毛片免费看| 亚洲国产另类久久久精品黑人| 国产亚洲精品久久久久久入口| 色99久久久久高潮综合影院| 国模无码大尺度一区二区三区| 97夜夜澡人人爽人人喊a| 18禁裸男晨勃露j毛网站| 中字乱码视频| 国产成人无码精品午夜福利a| 欧美亚洲日本国产综合在线 | 2020国产精品永久在线| 欧美丰满老熟妇乱叫| 婷婷成人综合激情在线视频播放| 国产偷人妻精品一区二区在线 | 99久热re在线精品99 6热视频| 小箩莉末发育娇小性色xxxx| 日本国产成人国产在线播放| 中文字幕乱码在线人视频| 欧美成人精品第一区二区三区| 亚洲αv无码一区二区三区四区| 狠狠色丁香久久婷婷综合_中| 97精品国产97久久久久久免费| 国产免费一区二区三区免费视频| 国产丰满麻豆vⅰde0sex| 无码人妻精品一区二区三区蜜桃| 国产综合在线观看| 亚洲午夜无码久久yy6080|