在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MIB2 Antibody, Biotin conjugated

  • 中文名稱:
    MIB2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA839291LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) MIB2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MIB2
  • 別名:
    MIB2 antibody; SKD antibody; ZZANK1 antibody; E3 ubiquitin-protein ligase MIB2 antibody; EC 2.3.2.27 antibody; Mind bomb homolog 2 antibody; Novel zinc finger protein antibody; Novelzin antibody; Putative NF-kappa-B-activating protein 002N antibody; RING-type E3 ubiquitin transferase MIB2 antibody; Skeletrophin antibody; Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase MIB2 protein (1-128AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
  • 基因功能參考文獻(xiàn):
    1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
    2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
    3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
    4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
    5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
    6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
    7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
    8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments.
  • 組織特異性:
    Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30577

    OMIM: 611141

    KEGG: hsa:142678

    STRING: 9606.ENSP00000426103

    UniGene: Hs.135805



主站蜘蛛池模板: 日本阿v网站在线观看中文| 欧美黑人添添高潮a片www| 中文无码vr最新无码av专区| 美女又黄又免费的视频| 成人看的污污超级黄网站免费| 高潮内射免费看片| 国产一卡三卡四卡无卡精品| 中国性欧美videofree精品| 国产av偷闻女邻居内裤被发现| 在线视频国产制服丝袜| 美女视频黄频a美女大全| 精品国产sm最大网站| 亚洲情xo亚洲色xo无码| 国产日韩另类综合11页| 久久精品国产只有精品66| 人妻av无码一区二区三区| 国产无遮挡裸体免费视频在线观看| 国偷自产一区二区免费视频| 欧美乱大交av片久久123| 人人揉揉揉香蕉大免费| 人妻无码熟妇乱又伦精品视频 | 亚洲 日本 欧美 中文幕| 精品国产欧美一区二区| 国产一区二区三区四区五区vm| 无码手机线免费观看| 日韩国产成人无码av毛片蜜柚| 国产高清在线精品一区下载 | 亚洲国产成人精品无码区在线| 国产精品视频| 看成年女人午夜毛片免费| 日本一二免费不卡区| 蜜桃传媒av免费观看麻豆| 久久伊人av综合影院| 女人大荫蒂毛茸茸视频| 国产高清不卡无码视频| 亚洲综合另类小说色区色噜噜| 久久久久成人片免费观看蜜芽| 亚洲精品久久久久久久久久吃药| а√天堂8资源中文在线| 日韩国产网曝欧美第一页| 欧美特大特白屁股ass|