在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MCM6 Antibody

MCM6 Antibody

  • 中文名稱：
    MCM6兔多克隆抗體
  • 貨號：
    CSB-PA013596GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA replication licensing factor MCM6 antibody; MCG40308 antibody; Mcm6 antibody; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe) antibody; MCM6 minichromosome maintenance deficient 6 antibody; MCM6_HUMAN antibody; Minichromosome maintenance complex component 6 antibody; Minichromosome maintenance deficient (mis5 S. pombe) 6 antibody; Minichromosome maintenance deficient 6 homolog antibody; Minichromosome maintenance protein 6 antibody; Mis5 antibody; MIS5 homolog antibody; p105MCM antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MCM6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • 基因功能參考文獻(xiàn)：
    1. Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. PMID: 27624874
    2. MCM6 is a highly reproducible marker of poor prognosis in endometrial cancer PMID: 29243125
    3. genetic association studies in population in Western Europe: Data confirm an SNP in MCM6 (rs4988235) is predictive of milk consumption; lack of association of genetically predicted milk consumption with prevention of osteoporosis, ischemic heart disease, or type 2 diabetes suggests few beneficial effects of milk consumption but is more consistent with milk promoting adiposity/overweight. PMID: 28225053
    4. Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma PMID: 26013954
    5. Report presence of homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase gene in lactose intolerant patients treated with lactose-restricted diet. PMID: 25651706
    6. Results indicate that the interaction between hCdt1 and hMcm6 through their interacting domains is key for hCdt1 in facilitating the MCM hetero-hexamer to load onto chromatin for replication licensing. PMID: 21099365
    7. The subtype and MCM6 protein expression in craniopharyngiomas are related to the prognosis of tumor. PMID: 17294730
    8. the molecular mechanism of Mcm2-7 chromatin loading and prereplicative complex assembly. PMID: 20202939
    9. The numbers of the three genotypic combinations reveal that the percentage of this population that is genetically lactose intolerant is 8.23% and that the allele frequencies found are consistent with the expected Mendelian distribution. PMID: 20173814
    10. Data show that cells subjected to chronic hypoxia the replicative restart was inhibited along with numerous replication factors including MCM6 and RPA, and cells reoxygenated after acute hypoxia underwent rapid p53-dependent apoptosis. PMID: 20103649
    11. It was found that the MCM6 label index (LI) was significantly higher in adamantine epithelioma than squamous papillary tumor, and in both primary tumor subtypes the LIs of tumors with recurrence were higher than those without recurrence. PMID: 17410335

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    MCM family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6949

    OMIM: 223100

    KEGG: hsa:4175

    STRING: 9606.ENSP00000264156

    UniGene: Hs.444118



主站蜘蛛池模板： 无码国产成人午夜电影在线观看| 欧美性生交活xxxxxdddd| 美女又大又黄www免费网站| 精品一区二区三区在线视频 | 国产成人精品无码播放| 99精品一区二区三区无码吞精| 国产99久久亚洲综合精品西瓜tv | 少妇一边呻吟一边说使劲视频| 久久精品无码一区二区日韩av| 国产精品jk白丝在线播放| av无码不卡一区二区三区| 中文字幕av无码一区二区三区 | 亚洲国产精品无码久久98| av在线亚洲男人的天堂| 国内精品乱码卡一卡2卡三卡新区 亚洲爆乳成av人在线视菜奈实 | 国产一区二区三区在线观看免费| 无码人妻精品一区二区在线视频| 加勒比无码人妻东京热| 三个男人躁我一个爽视频免费 | 少妇与大狼拘作爱性a| 国产拍拍拍无码视频免费| 国产免费无遮挡吸乳视频在线观看| 丰满少妇呻吟高潮经历| 亚洲婷婷五月综合狠狠爱| 日韩高清亚洲日韩精品一区| 在线观看国产精品乱码app| 国产精品自在拍在线拍| 欧洲熟妇色 欧美| 国产在线观看免费观看不卡| 中文无码人妻影音先锋| 国产熟女一区二区三区四区五区 | 国产美女露脸口爆吞精| 欧美日产国产精品| 国产午夜精品一区二区三区嫩草| av毛片无码中文字幕不卡 | 真人与拘做受免费视频一| 国产一区二区不卡老阿姨| 久久精品无码一区二区app| 国产av综合第一页| 97色偷偷色噜噜狠狠爱网站| 亚洲人成网站在线播放小说|