在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MCM6 Antibody

MCM6 Antibody

  • 中文名稱：
    MCM6兔多克隆抗體
  • 貨號：
    CSB-PA091656
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA091656(MCM6 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA091656(MCM6 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, K562 cells, NIH/3T3 cells, hela cells, Primary antibody: CSB-PA091656(MCM6 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA replication licensing factor MCM6 antibody; MCG40308 antibody; Mcm6 antibody; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe) antibody; MCM6 minichromosome maintenance deficient 6 antibody; MCM6_HUMAN antibody; Minichromosome maintenance complex component 6 antibody; Minichromosome maintenance deficient (mis5 S. pombe) 6 antibody; Minichromosome maintenance deficient 6 homolog antibody; Minichromosome maintenance protein 6 antibody; Mis5 antibody; MIS5 homolog antibody; p105MCM antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human MCM6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • 基因功能參考文獻(xiàn)：
    1. Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. PMID: 27624874
    2. MCM6 is a highly reproducible marker of poor prognosis in endometrial cancer PMID: 29243125
    3. genetic association studies in population in Western Europe: Data confirm an SNP in MCM6 (rs4988235) is predictive of milk consumption; lack of association of genetically predicted milk consumption with prevention of osteoporosis, ischemic heart disease, or type 2 diabetes suggests few beneficial effects of milk consumption but is more consistent with milk promoting adiposity/overweight. PMID: 28225053
    4. Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma PMID: 26013954
    5. Report presence of homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase gene in lactose intolerant patients treated with lactose-restricted diet. PMID: 25651706
    6. Results indicate that the interaction between hCdt1 and hMcm6 through their interacting domains is key for hCdt1 in facilitating the MCM hetero-hexamer to load onto chromatin for replication licensing. PMID: 21099365
    7. The subtype and MCM6 protein expression in craniopharyngiomas are related to the prognosis of tumor. PMID: 17294730
    8. the molecular mechanism of Mcm2-7 chromatin loading and prereplicative complex assembly. PMID: 20202939
    9. The numbers of the three genotypic combinations reveal that the percentage of this population that is genetically lactose intolerant is 8.23% and that the allele frequencies found are consistent with the expected Mendelian distribution. PMID: 20173814
    10. Data show that cells subjected to chronic hypoxia the replicative restart was inhibited along with numerous replication factors including MCM6 and RPA, and cells reoxygenated after acute hypoxia underwent rapid p53-dependent apoptosis. PMID: 20103649
    11. It was found that the MCM6 label index (LI) was significantly higher in adamantine epithelioma than squamous papillary tumor, and in both primary tumor subtypes the LIs of tumors with recurrence were higher than those without recurrence. PMID: 17410335

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    MCM family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6949

    OMIM: 223100

    KEGG: hsa:4175

    STRING: 9606.ENSP00000264156

    UniGene: Hs.444118



主站蜘蛛池模板： 九九视频在线观看视频6 | 成人免费的视频| 男女爽爽午夜18污污影院| 亚洲中文字幕在线精品2021| 蜜臀av999无码精品国产专区 | 韩国无码av片在线观看| 国产精品高潮呻吟av久久黄| 天天av天天翘天天综合网色鬼| 国产精品一区二区久久| 国产在线观看片a免费观看| 永久中文字幕免费视频网站| 一本大道伊人av久久综合| 亚洲人成人网站色www| 亚洲精品夜夜夜妓女网| 成人做受120秒试看试看视频| 精品免费看国产一区二区| 中文字幕亚洲欧美日韩在线不卡| 美女内射视频www网站午夜| 中文字幕人妻被公上司喝醉| 久久经精品久久精品免费观看| 中文字幕人乱码中文字幕| 欧美黑人性暴力猛交喷水黑人巨大| 玩弄丰满熟妇xxxxx性60| 久久精品亚洲综合专区 | 国产在线精品一区二区夜色| 欧美大片欧美激情性色a∨在线| 在线看亚洲十八禁网站| 成人欧美一区二区三区1314| 伊人久久成综合久久影院| 亚洲欧美日韩国产成人一区| 朝鲜女子内射杂交bbw| 老熟女五十路乱子交尾中出一区| 性色欲情网站iwww| 天天摸夜夜添狠狠添高潮出水| 亚洲欧洲日产国无高清码图片 | 精品久久久无码中文字幕 | 亚洲色爱免费观看视频| 国产白嫩美女在线观看| 亚洲国产成人av人片久久| 99热网址最新获取域名| 日韩少妇内射免费播放18禁裸乳|