在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MCM6 Antibody

MCM6 Antibody

  • 中文名稱：
    MCM6兔多克隆抗體
  • 貨號：
    CSB-PA005816
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HeLa cells using MCM6 Polyclonal Antibody .
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA replication licensing factor MCM6 antibody; MCG40308 antibody; Mcm6 antibody; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe) antibody; MCM6 minichromosome maintenance deficient 6 antibody; MCM6_HUMAN antibody; Minichromosome maintenance complex component 6 antibody; Minichromosome maintenance deficient (mis5 S. pombe) 6 antibody; Minichromosome maintenance deficient 6 homolog antibody; Minichromosome maintenance protein 6 antibody; Mis5 antibody; MIS5 homolog antibody; p105MCM antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MCM6 .
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • 基因功能參考文獻：
    1. Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. PMID: 27624874
    2. MCM6 is a highly reproducible marker of poor prognosis in endometrial cancer PMID: 29243125
    3. genetic association studies in population in Western Europe: Data confirm an SNP in MCM6 (rs4988235) is predictive of milk consumption; lack of association of genetically predicted milk consumption with prevention of osteoporosis, ischemic heart disease, or type 2 diabetes suggests few beneficial effects of milk consumption but is more consistent with milk promoting adiposity/overweight. PMID: 28225053
    4. Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma PMID: 26013954
    5. Report presence of homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase gene in lactose intolerant patients treated with lactose-restricted diet. PMID: 25651706
    6. Results indicate that the interaction between hCdt1 and hMcm6 through their interacting domains is key for hCdt1 in facilitating the MCM hetero-hexamer to load onto chromatin for replication licensing. PMID: 21099365
    7. The subtype and MCM6 protein expression in craniopharyngiomas are related to the prognosis of tumor. PMID: 17294730
    8. the molecular mechanism of Mcm2-7 chromatin loading and prereplicative complex assembly. PMID: 20202939
    9. The numbers of the three genotypic combinations reveal that the percentage of this population that is genetically lactose intolerant is 8.23% and that the allele frequencies found are consistent with the expected Mendelian distribution. PMID: 20173814
    10. Data show that cells subjected to chronic hypoxia the replicative restart was inhibited along with numerous replication factors including MCM6 and RPA, and cells reoxygenated after acute hypoxia underwent rapid p53-dependent apoptosis. PMID: 20103649
    11. It was found that the MCM6 label index (LI) was significantly higher in adamantine epithelioma than squamous papillary tumor, and in both primary tumor subtypes the LIs of tumors with recurrence were higher than those without recurrence. PMID: 17410335

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    MCM family
  • 數據庫鏈接：

    HGNC: 6949

    OMIM: 223100

    KEGG: hsa:4175

    STRING: 9606.ENSP00000264156

    UniGene: Hs.444118



主站蜘蛛池模板： 国产精品午夜福利不卡| 脱岳裙子从后面挺进去在线观看| 久99久无码精品视频免费播放| 午夜尤物禁止18点击进入| 四虎www永久在线精品| 欧美老熟妇乱xxxxx| 97人妻精品一区二区三区| 漂亮人妻熟睡中被公侵犯中文版| 性中国妓女毛茸茸视频| 亚洲精品久久久www小说| 少妇一边呻吟一边说使劲视频| 亚洲国色天香卡2卡3卡4| 一区二区三区鲁丝不卡麻豆 | 日韩一区二区三免费高清| 人人爽天天碰天天躁夜夜躁| 精品久久久久久无码人妻| 在线播放人成视频观看| 亚洲乱码中文字幕手机在线| 亚洲春色在线视频| 亚洲va无码专区国产乱码| 亚洲男人片片在线观看| 成人免费无码大片a毛片抽搐| 久久综合伊人77777| 丁香婷婷综合久久来来去| 夜夜躁狠狠躁日日躁2022| 亚洲多毛妓女毛茸茸的| 乱中年女人伦av| 97精品免费公开在线视频| 国产三级精品三级在线观看| 少妇伦子伦情品无吗| 狠狠久久久久综合成人影院| 伊人婷婷六月狠狠狠去| 搡老岳熟女国产熟妇| 中文字幕熟妇人妻在线视频| 特级a欧美做爰片第一次| 免费又黄又硬又爽大片| 国产真实交换配乱婬95视频| 激情文学小说区另类小说同性| 国产呻吟久久久久久久92| 东京道一本热中文字幕| 日韩亚洲国产综合高清|