在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MCM6 Antibody

MCM6 Antibody

  • 中文名稱：
    MCM6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA618894ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DNA replication licensing factor MCM6 antibody at 3μg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 93 kDa
      Observed band size: 93 kDa
    • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA618894ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA618894ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MCM6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA replication licensing factor MCM6 antibody; MCG40308 antibody; Mcm6 antibody; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe) antibody; MCM6 minichromosome maintenance deficient 6 antibody; MCM6_HUMAN antibody; Minichromosome maintenance complex component 6 antibody; Minichromosome maintenance deficient (mis5 S. pombe) 6 antibody; Minichromosome maintenance deficient 6 homolog antibody; Minichromosome maintenance protein 6 antibody; Mis5 antibody; MIS5 homolog antibody; p105MCM antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human DNA replication licensing factor MCM6 protein (562-821AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • 基因功能參考文獻(xiàn)：
    1. Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. PMID: 27624874
    2. MCM6 is a highly reproducible marker of poor prognosis in endometrial cancer PMID: 29243125
    3. genetic association studies in population in Western Europe: Data confirm an SNP in MCM6 (rs4988235) is predictive of milk consumption; lack of association of genetically predicted milk consumption with prevention of osteoporosis, ischemic heart disease, or type 2 diabetes suggests few beneficial effects of milk consumption but is more consistent with milk promoting adiposity/overweight. PMID: 28225053
    4. Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma PMID: 26013954
    5. Report presence of homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase gene in lactose intolerant patients treated with lactose-restricted diet. PMID: 25651706
    6. Results indicate that the interaction between hCdt1 and hMcm6 through their interacting domains is key for hCdt1 in facilitating the MCM hetero-hexamer to load onto chromatin for replication licensing. PMID: 21099365
    7. The subtype and MCM6 protein expression in craniopharyngiomas are related to the prognosis of tumor. PMID: 17294730
    8. the molecular mechanism of Mcm2-7 chromatin loading and prereplicative complex assembly. PMID: 20202939
    9. The numbers of the three genotypic combinations reveal that the percentage of this population that is genetically lactose intolerant is 8.23% and that the allele frequencies found are consistent with the expected Mendelian distribution. PMID: 20173814
    10. Data show that cells subjected to chronic hypoxia the replicative restart was inhibited along with numerous replication factors including MCM6 and RPA, and cells reoxygenated after acute hypoxia underwent rapid p53-dependent apoptosis. PMID: 20103649
    11. It was found that the MCM6 label index (LI) was significantly higher in adamantine epithelioma than squamous papillary tumor, and in both primary tumor subtypes the LIs of tumors with recurrence were higher than those without recurrence. PMID: 17410335

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    MCM family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 6949

    OMIM: 223100

    KEGG: hsa:4175

    STRING: 9606.ENSP00000264156

    UniGene: Hs.444118



主站蜘蛛池模板： 无码人妻精一区二区三区| 日本一道本高清一区二区| 国产999久久高清免费观看 | 无码一区二区三区av在线播放 | 高清国产亚洲欧洲av综合一区| 亚洲a∨无码国产精品久久网| 色欲综合一区二区三区| 黑森林福利视频导航| 大陆熟妇丰满多毛xxxⅹ| 亚洲色成人四虎在线观看| 99久久国产露脸精品竹菊传媒| 浪潮av色综合久久天堂| 狠狠躁夜夜躁人人爽天天天天97 | 中国少妇videos呻吟| 无码国模国产在线观看| 国产成人精品无码免费看夜聊软件| 成人欧美一区二区三区在线观看| 国产精品亚洲w码日韩中文| 亚洲无人区午夜福利码高清完整版 | 国外亚洲成av人片在线观看| 18禁成人网站免费观看| 日韩av无码成人无码免费| 女狠狠噜天天噜日日噜| 午夜福利av无码一区二区| 国产在线精品视频免费观看| 日本丰满熟妇bbxbbxhd| 狠狠色狠狠色综合网老熟女| 亚洲精品久久久久中文字幕m男 | 久激情内射婷内射蜜桃人妖| 97精品尹人久久大香线蕉 | 无码免费中文字幕视频| 国产欧美日韩一区二区三区| 亚洲无线码在线一区观看| 欧美不卡无线在线一二三区观| 亚洲欧美中文字幕高清在线| 影视先锋av资源噜噜| 免费观看的av在线播放| 熟女丝袜潮喷内裤视频网站| 精品久久人妻av中文字幕| 日韩一区二区三区精品| 97在线成人国产在线视频 |