在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOOK3 Antibody, FITC conjugated

HOOK3 Antibody, FITC conjugated

  • 中文名稱：
    HOOK3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA769790LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOOK3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOOK3
  • 別名：
    FLJ31058 antibody; h-hook3 antibody; hHK3 antibody; HK3 antibody; hook3 antibody; HOOK3_HUMAN antibody; OTTHUMP00000229200 antibody; Protein Hook homolog 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein Hook homolog 3 protein (357-455AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.; (Microbial infection) May serve as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking.
  • 基因功能參考文獻：
    1. This work reveals the structural details of Hook3's interaction with dynein and offers insight into how cargo adaptors form processive dynein-dynactin motor complexes. PMID: 27482052
    2. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2). PMID: 27365401
    3. results of our study identify HOOK3 as a strong candidate prognostic marker with a possible role in maintaining genomic integrity in prostate cancer, which may have potential for inclusion into clinical routine assays PMID: 26230842
    4. Results found that downregulation of Hook3 expression slows down endosomal transport and increases beta-amyloid production suggesting that Hook3 might play a critical role in pathogenic events exacerbating Alzheimer disease. PMID: 25799409
    5. Hook3 is recruited to pericentriolar satellites through interaction with pericentriolar material 1 protein PCM1. PMID: 20152126
    6. Salmonella SpiC targets the function of Hook3, a mammalian protein implicated in cellular trafficking. PMID: 12950921
    7. Hook3 interacts with a cytoplasmic domain of scavenger receptor A PMID: 17237231
    8. A fusion product between exon 11 of HOOK3 and exon 12 of RET gene was identified by 5'RACE, and the presence of chimeric HOOK3-RET protein of 88 kDa was detected by western blot analysis with an anti-RET antibody. PMID: 17639057

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Golgi apparatus.
  • 蛋白家族：
    Hook family
  • 數據庫鏈接：

    HGNC: 23576

    OMIM: 607825

    KEGG: hsa:84376

    STRING: 9606.ENSP00000305699

    UniGene: Hs.162852



主站蜘蛛池模板： 无码高潮爽到爆的喷水视频| 亚洲日韩中文第一精品| 一个人在线观看免费中文www| 中文字幕亚洲色妞精品天堂| 日产精品高潮呻吟av久久| 在线高清亚洲精品二区| 色777狠狠狠综合| 麻豆精品传媒一二三区艾秋| 国产精品无码无卡在线播放| 一本大道东京热无码aⅴ| 黄网站欧美内射| 成人啪啪高潮不断观看| 久久久久久人妻毛片a片| 国产性夜夜春夜夜爽免费下载 | 巨大乳做爰视频在线看| 欧洲无线码免费一区| 99热精国产这里只有精品| 精品欧美一区二区在线观看| 国产精品无码久久久久久久久久| av中文字幕潮喷人妻系列| 欧洲日本一线二线三线区本庄铃 | 亚洲国产成人精品福利| 人人爽久久久噜噜噜婷婷| 欧美性大战久久久久xxx| 波多野结av衣东京热无码专区| 美女张开腿让人桶| 精品少妇人妻av久久久| 午夜爱爱爱爱爽爽爽网站| 大色综合色综合网站| 亚洲人成网站18禁止无码| 中文乱码字幕视频观看网站免费 | 中文韩国午夜理伦三级好看| 国产超碰人人做人人爽av | 欧美人与性动交g欧美精器| 瑜伽裤国产一区二区三区| 无码h肉动漫在线观看免费 | 国产日韩在线视看第一页 | 国产精品亚洲色婷婷99久久精品| b站永久免费看片大全| 亚洲成av大片大片在线播放| 亚洲色www成人永久网址|