在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-63) Antibody

  • 中文名稱:
    HIST1H1E (Ab-63)兔多克隆抗體
  • 貨號(hào):
    CSB-PA010380PA63nme1HU
  • 規(guī)格:
    ¥660
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA010380PA63nme1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010380PA63nme1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (63) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻(xiàn):
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Rahman syndrome (RMNS)
  • 亞細(xì)胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 成人夜色视频网站在线观看| 狠狠躁日日躁夜夜躁2022麻豆| 久久精品2021国产| 国产精品无码a∨果冻传媒| 一区二区三区av高清免费波多| 国产一区日韩二区欧美三区| 国产97色在线 | 免费| 亚洲a成人无码网站在线| 国产av丝袜一区二区三区| 人妻巨大乳hd免费看| 国内精品伊人久久久久7777| 七七久久成人影院网站| 国产明星xxxx色视频| 欧美精品无码一区二区三区| 免费观看激色视频网站| 日本道免费精品一区二区| 国产亚洲精品a片久久久| 精品国产av 无码一区二区三区| 女人张开腿让男人桶爽| 久久成人国产精品无码| 久久久99久久久国产自输拍| 97久久国产亚洲精品超碰热 | 丝袜 亚洲 另类 欧美 变态 | 国产成人av性色在线影院色戒| 国产午夜精品一区二区三区| 成人区人妻精品一区二区不卡视频| 精品久久欧美熟妇www| 国产精品无码av不卡顿| 亚洲精品乱码久久久久久蜜桃| 国产精品制服| 中美日韩毛片免费播放 | 午夜福利体验免费体验区| 国内精品久久久久影院优| 久久99热狠狠色精品一区| 狠狠色狠狠色综合久久| 欧美性xxxx极品hd欧美风情| 大伊香蕉精品视频在线 | 欧美日韩人人模人人爽人人喊| 日韩精品一卡2卡3卡4卡新区| 在线观看国产亚洲视频免费| 又粗又大又硬毛片免费看|