在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-62) Antibody

  • 中文名稱:
    HIST1H1E (Ab-62)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA62nforHU
  • 規格:
    ¥660
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, U87 whole cell lysate, K562 whole cell lysate
      All lanes: HIST1H1E antibody at 1.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
    • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA010380PA62nforHU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA010380PA62nforHU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (62) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 色噜噜噜亚洲男人的天堂| 国产情侣草莓视频在线| 国产精品国产对白熟妇| 亚洲 熟女 久久 国产| 精品午夜福利在线观看| 777精品久无码人妻蜜桃| 亚洲国产日韩在线人成蜜芽| 精品无码国模私拍视频| 日本高清视频在线www色| 精品一区二区三区无码免费视频| 偷窥国产亚洲免费视频| 婷婷网色偷偷亚洲男人甘肃| 精品久久久无码人妻中文字幕| 精品一卡二卡三卡| 护士张开腿被奷日出白浆| 一边捏奶一边高潮视频| 午夜男女爽爽影院免费视频下载| 国产美女被遭高潮免费视频 | 真实国产熟睡乱子伦视频| 午夜无码人妻av大片色欲| 97人人模人人爽人人少妇| 国产乱码免费卡1卡二卡3| 国产高清露脸孕妇系列| 国产成年无码久久久久毛片| 亚洲欧美日韩国产精品一区二区 | 国产女人抽搐喷浆视频| 成年美女黄网站色奶头大全| 在线播放无码后入内射少妇| 四川骚妇无套内射舔了更爽| 亚洲午夜福利在线视频| 欧美亚洲色综久久精品国产| 女人被躁到高潮免费视频| 国产精品无码久久四虎| 欧美老妇交乱视频在线观看 | 少妇一边呻吟一边说使劲视频 | 国产精品成人片在线观看| 男女高潮喷水在线观看| 中文无码乱人伦中文视频在线v| 2012中文字幕在线视频| 国产1卡二卡3卡四卡乱码视频| 国产精品av在线|