在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-62) Antibody

  • 中文名稱:
    HIST1H1E (Ab-62)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA62nforHU
  • 規格:
    ¥660
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, U87 whole cell lysate, K562 whole cell lysate
      All lanes: HIST1H1E antibody at 1.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
    • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA010380PA62nforHU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA010380PA62nforHU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (62) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 精品国产福利拍拍拍| 曰本极品少妇videossexhd| 老师黑色丝袜被躁翻了av| 久久这里只有是精品23| 亚洲精品毛片一区二区三区| 久久国产高潮流白浆免费观看| 男女性高爱潮免费网站| 国内精品国产三级国产av| 无码av一区二区大桥久未| 国产在线观看无码不卡| 久爱www成人网免费视频| 日本伊人色综合网| 亚洲综合另类小说色区| 又爆又大又粗又硬又黄的a片| 久久久久久久综合日本| 国产成人无码www免费视频播放 | 精品服丝袜无码视频一区| 欧美精品无码久久久久久| 亚洲成av人片不卡无码| 国产成人av综合久久| 成年片色大黄全免费网站久久| 加勒比东京热无码一区| 乱熟女高潮一区二区在线| 国产亚洲精品久久久久秋霞不卡| 精产国品一二三产品麻豆| 成人性做爰aaa片免费| 少妇无码一区二区二三区| 国产精品女人呻吟在线观看| 韩国精品视频一区二区在线播放| 中文字幕人成乱码熟女免费| 亚洲人成伊人成综合网中文| 日韩高清在线观看永久| 国产热の有码热の无码视频| 国产欧美日韩综合精品一区二区| 久久亚洲一区二区三区四区| 国产精品www夜色视频| 色先锋资源久久综合5566| 中文字幕av无码人妻| 一本一道久久a久久精品综合| 无码中文字幕日韩专区| 日本午夜看x费免|