在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-51) Antibody

  • 中文名稱(chēng):
    HIST1H1E (Ab-51)兔多克隆抗體
  • 貨號(hào):
    CSB-PA010380PA51nacHU
  • 規(guī)格:
    ¥660
  • 圖片:
    • Immunofluorescent analysis of Hela cells using CSB-PA010380PA51nacHU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (51) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻(xiàn):
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Rahman syndrome (RMNS)
  • 亞細(xì)胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 成熟妇女性成熟满足视频| 免费无码观看的av在线播放| 337p日本大胆欧美裸体艺术| 国产亚洲精品久久久久久老妇小说 | 亚洲婷婷开心色四房播播| 色午夜日本高清视频www| 精品久久久久久| 色五月丁香五月综合五月4438| 亚洲成片在线观看12345| a毛片终身免费观看网站| 国产精品无码制服丝袜| 中国熟妇浓毛hdsex| 久久青草成人综合网站| 国产内射爽爽大片| 日产一区日产2区| 激情偷乱人伦小说视频| 顶级欧美熟妇高潮xxxxx| аⅴ资源天堂资源库在线| 日本精品一区二区三区四区| 最新国产久免费视频在线观看 | 久久综合色鬼综合色| 国内午夜国产精品小视频| 久久久久人妻一区精品果冻 | av蓝导航精品导航| 亚洲国产欧美在线人成aaaa| 性色av蜜臀av色欲av| 亚洲欧洲无卡二区视頻| 国产美女视频免费观看网址| 亚洲午夜成人av电影| 精品亚洲一区二区三区四区五区 | 性xxxxx大片免费视频| 久久精品亚洲乱码伦伦中文| 国产又色又爽又黄的免费| 欧美性猛交xxxx免费视频软件 | 国产精品亚洲а∨天堂| 国产成人涩涩涩视频在线观看| 无码一区二区三区av免费| 在线无码免费的毛片视频| 就去干成人网| 麻豆国产97在线 | 欧美| 亚洲人成网线在线播放|