在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-16) Antibody

  • 中文名稱:
    HIST1H1E (Ab-16)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA16nacHU
  • 規格:
    ¥660
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, K562 whole cell lysate
      All lanes: HIST1H1E antibody at 0.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA010380PA16nacHU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA010380PA16nacHU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (16) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:100-1:1000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 国产美女裸身网站免费观看视频| 欧美激情在线播放| 欧美亚洲国产精品久久高清 | 亚洲精品国产精华液| 国产精品无码素人福利| 99久久国产露脸精品国产麻豆| 成+人+网+站+免费观看| 亚洲中文综合网五月俺也去| 97久久草草超级碰碰碰| 国产激情з∠视频一区二区| 亚洲国产成人久久一区www| 在线不卡日本v一区二区| 国产精品美女久久久久久2021| 少妇愉情理伦片丰满丰满| 天美麻花果冻视频大全英文版| 久久99精品久久久久久噜噜 | 欧美亚洲日本国产黑白配| 国产精品久久精品第一页| 国产a∨精品一区二区三区不卡 | 欧美成人精精品一区二区| 亚洲.日韩.欧美另类| 又粗又大又黄又爽的免费视频| 丰满多毛的大隂户视频| 两个美女裸体舌吻互扒内裤| 2021精品亚洲中文字幕| 免费无码一区二区三区a片百度| 色丁香婷婷综合久久| 高清情侣国语自产拍| 亚洲国产一成人久久精品| 国产高清在线精品一区免费| 精品国产制服丝袜高跟| 国产又猛又黄又爽| 日韩经典精品无码一区| 蜜柚av久久久久久久| 亚洲中文字幕无码久久2017 | 亚洲国产长腿丝袜av天堂| 成a人片亚洲日本久久| 无码av免费一区二区三区a片| 亚洲综合另类小说专区| 男女作爱免费网站| 成片免费观看视频大全|