在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-16) Antibody

  • 中文名稱:
    HIST1H1E (Ab-16)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA16nacHU
  • 規格:
    ¥660
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, K562 whole cell lysate
      All lanes: HIST1H1E antibody at 0.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA010380PA16nacHU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA010380PA16nacHU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (16) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:100-1:1000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 四虎国产成人永久精品免费| 中文在线天堂а√在线| 大白肥妇bbvbbw高潮| 精品国产av无码一区二区三区| 国产人妻久久精品二区三区特黄 | 精品久久亚洲中文无码| 日产精品高潮呻吟av久久| 久久亚洲人成电影网| 99精品视频在线观看免费蜜桃| 女女互磨互喷水高潮les呻吟| 国产熟妇勾子乱视频| 天天狠天天透天干天天| 中日韩产精品1卡二卡三卡| 国产人妖xxxx做受视频| а√天堂资源中文在线官网| 日本少妇内射视频播放舔| 久久久久国色av免费观看性色 | 人妻夜夜爽天天爽三区| 亚洲高清乱码午夜电影网| 成人无码av网站在线观看| 性做久久久久久久免费看| 欧美熟妇xxxxx欧美老妇不卡| 九九热线有精品视频| 天堂亚洲国产中文在线| 亚洲人成无码网站| 亚洲国产美女精品久久久久∴ | 秋霞午夜鲁丝片午夜精品| 成年入口无限观看免费完整大片 | 波多野42部无码喷潮在线| 高潮爽死抽搐白浆gif视频| 久久精品女人天堂av免费观看| 亚洲中文字幕久久无码| 成人免费无遮挡在线播放| 蜜桃少妇av久久久久久久| 久久综合久久久久88| 中文在线中文a| 国产美女视频免费观看网址| 日本精品人妻无码免费大全| 高大丰满熟妇丰满的大白屁股| 国产乱人伦偷精品视频下| 免费毛儿一区二区十八岁|