在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-147) Antibody

  • 中文名稱:
    HIST1H1E (Ab-147)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA147nme1HU
  • 規格:
    ¥660
  • 圖片:
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA010380PA147nme1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (147) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 无翼乌工口全彩肉肉无遮挡18| 国产精品自在欧美一区| 日本熟妇大乳| 亚洲欧洲日产韩国在线看片| 国精产品48x国精产品| 成人无码精品一区二区三区亚洲区| 亚洲国产无线乱码在线观看| 亚洲精品人成网线在线播放va| 国产成人8x人网站视频在线观看| 性饥渴的农村熟妇| h肉动漫无码无修6080动漫网| 国产在线精品无码不卡手机免费| 中老年熟妇激情啪啪大屁股| 一本色道久久88加勒比—综合| 国产情侣真实露脸在线| 在线播放十八禁视频无遮挡| 一本av高清一区二区三区| 亚洲人成色77777在线观看大战| 亚洲色www永久网站| 色播亚洲视频在线观看| 国产精品久久人妻无码网站蜜臀| 国产精品人妻一区二区高| 中出内射颜射骚妇| 国产亚洲高清国产拍精品| 天堂va欧美ⅴa亚洲va| 国产精品熟妇一区二区三区四区| 无码人妻一区二区三区免费n鬼沢| 亚洲成av人片在www| 在线看免费无码av天堂的| 一本大道东京热无码aⅴ| 又爽又黄无遮拦成人网站| 国产av麻豆天堂亚洲国产av刚刚碰| 成年女人黄小视频| 三级视频兔费看| 最近中文字幕免费mv在线| 国产亚洲精品a在线观看下载| 久久久久久自慰出白浆| 新国产精品视频福利免费| 国产精品禁18久久久夂久| 久久久久成人精品免费播放动漫 | 52综合精品国产二区无码|